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3t95

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[[Image:3t95.png|left|200px]]
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==Crystal structure of LsrB from Yersinia pestis complexed with autoinducer-2==
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<StructureSection load='3t95' size='340' side='right' caption='[[3t95]], [[Resolution|resolution]] 1.75&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[3t95]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Yersinia_pestis Yersinia pestis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3T95 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3T95 FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PAV:(2R,4S)-2-METHYL-2,3,3,4-TETRAHYDROXYTETRAHYDROFURAN'>PAV</scene><br>
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<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1tjy|1tjy]], [[3ejw|3ejw]], [[1tm2|1tm2]]</td></tr>
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<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">lsrB, y3772, YPO0409, YP_3772 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=632 Yersinia pestis])</td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3t95 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3t95 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3t95 RCSB], [http://www.ebi.ac.uk/pdbsum/3t95 PDBsum]</span></td></tr>
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<table>
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<div style="background-color:#fffaf0;">
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== Publication Abstract from PubMed ==
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The crystal structure of LsrB from Yersinia pestis complexed with autoinducer-2 (AI-2; space group P2(1)2(1)2(1), unit-cell parameters a = 40.61, b = 61.03, c = 125.23 A) has been solved by molecular replacement using the structure of LsrB from Salmonella typhimurium (PDB entry 1tjy) and refined to R = 0.180 (R(free) = 0.213) at 1.75 A resolution. The electron density for bound AI-2 and the stereochemistry of the AI-2-binding site are consistent with bound AI-2 adopting the (2R,4S)-2-methyl-2,3,3,4-tetrahydroxytetrahydrofuran conformation, just as has been observed in the crystal structures of the Salmonella typhimurium and Sinorhizobium meliloti LsrB-AI-2 complexes.
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The structure of LsrB from Yersinia pestis complexed with autoinducer-2.,Kavanaugh JS, Gakhar L, Horswill AR Acta Crystallogr Sect F Struct Biol Cryst Commun. 2011 Dec 1;67(Pt 12):1501-5., Epub 2011 Nov 29. PMID:22139152<ref>PMID:22139152</ref>
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The line below this paragraph, containing "STRUCTURE_3t95", creates the "Structure Box" on the page.
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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or leave the SCENE parameter empty for the default display.
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{{STRUCTURE_3t95| PDB=3t95 | SCENE= }}
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===Crystal structure of LsrB from Yersinia pestis complexed with autoinducer-2===
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
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</div>
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== References ==
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<!--
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<references/>
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The line below this paragraph, {{ABSTRACT_PUBMED_22139152}}, adds the Publication Abstract to the page
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__TOC__
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(as it appears on PubMed at http://www.pubmed.gov), where 22139152 is the PubMed ID number.
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</StructureSection>
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{{ABSTRACT_PUBMED_22139152}}
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==About this Structure==
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[[3t95]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Yersinia_pestis Yersinia pestis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3T95 OCA].
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==Reference==
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<ref group="xtra">PMID:022139152</ref><references group="xtra"/>
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[[Category: Yersinia pestis]]
[[Category: Yersinia pestis]]
[[Category: Gakhar, L.]]
[[Category: Gakhar, L.]]

Revision as of 06:10, 5 June 2014

Crystal structure of LsrB from Yersinia pestis complexed with autoinducer-2

3t95, resolution 1.75Å

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