3zse

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[[Image:3zse.png|left|200px]]
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==3D Structure of a thermophilic family GH11 xylanase from Thermobifida fusca==
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<StructureSection load='3zse' size='340' side='right' caption='[[3zse]], [[Resolution|resolution]] 1.78&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[3zse]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermobifida_fusca Thermobifida fusca]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZSE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ZSE FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=FXP:2-DEOXY-2-FLUORO-4-O-BETA-D-XYLOPYRANOSYL-ALPHA-D-XYLOPYRANOSE'>FXP</scene><br>
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<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Endo-1,4-beta-xylanase Endo-1,4-beta-xylanase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.8 3.2.1.8] </span></td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3zse FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zse OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3zse RCSB], [http://www.ebi.ac.uk/pdbsum/3zse PDBsum]</span></td></tr>
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<table>
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<div style="background-color:#fffaf0;">
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== Publication Abstract from PubMed ==
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Thermostable enzymes employ various structural features dictated at the amino-acid sequence level that allow them to maintain their integrity at higher temperatures. Many hypotheses as to the nature of thermal stability have been proposed, including optimized core hydrophobicity and an increase in charged surface residues to enhance polar solvent interactions for solubility. Here, the three-dimensional structure of the family GH11 xylanase from the moderate thermophile Thermobifida fusca in its trapped covalent glycosyl-enzyme intermediate complex is presented. Interactions with the bound ligand show fewer direct hydrogen bonds from ligand to protein than observed in previous complexes from other species and imply that binding of the xylan substrate involves several water-mediated hydrogen bonds.
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Three-dimensional structure of a thermophilic family GH11 xylanase from Thermobifida fusca.,van Bueren AL, Otani S, Friis EP, Wilson KS, Davies GJ Acta Crystallogr Sect F Struct Biol Cryst Commun. 2012 Feb 1;68(Pt 2):141-4. Epub, 2012 Jan 25. PMID:22297985<ref>PMID:22297985</ref>
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The line below this paragraph, containing "STRUCTURE_3zse", creates the "Structure Box" on the page.
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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or leave the SCENE parameter empty for the default display.
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{{STRUCTURE_3zse| PDB=3zse | SCENE= }}
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===3D Structure of a thermophilic family GH11 xylanase from Thermobifida fusca===
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
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</div>
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== References ==
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<references/>
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The line below this paragraph, {{ABSTRACT_PUBMED_22297985}}, adds the Publication Abstract to the page
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__TOC__
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(as it appears on PubMed at http://www.pubmed.gov), where 22297985 is the PubMed ID number.
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</StructureSection>
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{{ABSTRACT_PUBMED_22297985}}
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==About this Structure==
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[[3zse]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermobifida_fusca Thermobifida fusca]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZSE OCA].
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==Reference==
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<ref group="xtra">PMID:022297985</ref><references group="xtra"/>
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[[Category: Endo-1,4-beta-xylanase]]
[[Category: Endo-1,4-beta-xylanase]]
[[Category: Thermobifida fusca]]
[[Category: Thermobifida fusca]]

Revision as of 07:12, 5 June 2014

3D Structure of a thermophilic family GH11 xylanase from Thermobifida fusca

3zse, resolution 1.78Å

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