5msf

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{{Seed}}
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==MS2 PROTEIN CAPSID/RNA COMPLEX==
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[[Image:5msf.png|left|200px]]
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<StructureSection load='5msf' size='340' side='right' caption='[[5msf]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[5msf]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/Enterobacterio_phage_ms2 Enterobacterio phage ms2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5MSF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5MSF FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">COAT PROTEIN ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=12022 Enterobacterio phage MS2])</td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5msf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5msf OCA], [http://www.rcsb.org/pdb/explore.do?structureId=5msf RCSB], [http://www.ebi.ac.uk/pdbsum/5msf PDBsum]</span></td></tr>
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<table>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ms/5msf_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
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<div style="clear:both"></div>
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<div style="background-color:#fffaf0;">
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== Publication Abstract from PubMed ==
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We have determined the crystal structures, at 2.8 A resolution, of two different RNA aptamers, each bound to MS2 coat protein. One of the aptamers contains a non-Watson-Crick base pair, while the other is missing one of the unpaired adenines that make sequence-specific contacts in the wild-type complex. Despite these differences, the RNA aptamers bind in the same location on the protein as the wild-type translational operator. Comparison of these new structures with other MS2-RNA complexes allows us to refine further the definition of the minimal recognition elements and suggests a possible application of the MS2 system for routine structure determination of small nucleic acid motifs.
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<!--
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Crystal structures of a series of RNA aptamers complexed to the same protein target.,Rowsell S, Stonehouse NJ, Convery MA, Adams CJ, Ellington AD, Hirao I, Peabody DS, Stockley PG, Phillips SE Nat Struct Biol. 1998 Nov;5(11):970-5. PMID:9808042<ref>PMID:9808042</ref>
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The line below this paragraph, containing "STRUCTURE_5msf", creates the "Structure Box" on the page.
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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or leave the SCENE parameter empty for the default display.
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-->
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{{STRUCTURE_5msf| PDB=5msf | SCENE= }}
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===MS2 PROTEIN CAPSID/RNA COMPLEX===
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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</div>
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== References ==
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<!--
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<references/>
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The line below this paragraph, {{ABSTRACT_PUBMED_9808042}}, adds the Publication Abstract to the page
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__TOC__
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(as it appears on PubMed at http://www.pubmed.gov), where 9808042 is the PubMed ID number.
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</StructureSection>
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-->
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{{ABSTRACT_PUBMED_9808042}}
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==About this Structure==
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5MSF is a 5 chains structure with sequences from [http://en.wikipedia.org/wiki/Enterobacterio_phage_ms2 Enterobacterio phage ms2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5MSF OCA].
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==Reference==
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<ref group="xtra">PMID:9808042</ref><references group="xtra"/>
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[[Category: Enterobacterio phage ms2]]
[[Category: Enterobacterio phage ms2]]
[[Category: Adams, C J.]]
[[Category: Adams, C J.]]
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[[Category: Stonehouse, N J.]]
[[Category: Stonehouse, N J.]]
[[Category: Bacteriophage ms2]]
[[Category: Bacteriophage ms2]]
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[[Category: Capsid protein ms2/rna aptamer complex]]
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[[Category: Capsid protein ms2-rna aptamer complex]]
[[Category: Icosahedral virus]]
[[Category: Icosahedral virus]]
[[Category: Rna stem loop]]
[[Category: Rna stem loop]]
[[Category: Rna-protein complex]]
[[Category: Rna-protein complex]]
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[[Category: Virus/rna complex]]
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[[Category: Virus-rna complex]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Sep 22 11:31:29 2010''
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Revision as of 07:32, 5 June 2014

MS2 PROTEIN CAPSID/RNA COMPLEX

5msf, resolution 2.80Å

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Proteopedia Page Contributors and Editors (what is this?)

OCA

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