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4eqz

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[[Image:4eqz.jpg|left|200px]]
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==Crystal structure of human DOT1L in complex with inhibitor FED2==
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<StructureSection load='4eqz' size='340' side='right' caption='[[4eqz]], [[Resolution|resolution]] 2.15&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4eqz]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4EQZ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4EQZ FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=AW0:5-DEOXY-5-[(3-{[(4-METHYLPHENYL)CARBAMOYL]AMINO}PROPYL)(PROPAN-2-YL)AMINO]ADENOSINE'>AW0</scene>, <scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene><br>
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<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4er0|4er0]], [[4er3|4er3]], [[4er5|4er5]], [[4er6|4er6]], [[4er7|4er7]]</td></tr>
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<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">DOT1L, KIAA1814, KMT4 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
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<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Histone-lysine_N-methyltransferase Histone-lysine N-methyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.43 2.1.1.43] </span></td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4eqz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4eqz OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4eqz RCSB], [http://www.ebi.ac.uk/pdbsum/4eqz PDBsum]</span></td></tr>
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<table>
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==See Also==
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The line below this paragraph, containing "STRUCTURE_4eqz", creates the "Structure Box" on the page.
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*[[Histone methyltransferase|Histone methyltransferase]]
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__TOC__
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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</StructureSection>
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{{STRUCTURE_4eqz| PDB=4eqz | SCENE= }}
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===Crystal structure of human DOT1L in complex with inhibitor FED2===
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==About this Structure==
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[[4eqz]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4EQZ OCA].
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[[Category: Histone-lysine N-methyltransferase]]
[[Category: Histone-lysine N-methyltransferase]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]

Revision as of 08:01, 5 June 2014

Crystal structure of human DOT1L in complex with inhibitor FED2

4eqz, resolution 2.15Å

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