1bev
From Proteopedia
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| - | [[Image:1bev.gif|left|200px]] | + | [[Image:1bev.gif|left|200px]] |
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| - | '''BOVINE ENTEROVIRUS VG-5-27''' | + | {{Structure |
| + | |PDB= 1bev |SIZE=350|CAPTION= <scene name='initialview01'>1bev</scene>, resolution 3.0Å | ||
| + | |SITE= | ||
| + | |LIGAND= <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene> and <scene name='pdbligand=MYR:MYRISTIC ACID'>MYR</scene> | ||
| + | |ACTIVITY= | ||
| + | |GENE= | ||
| + | }} | ||
| + | |||
| + | '''BOVINE ENTEROVIRUS VG-5-27''' | ||
| + | |||
==Overview== | ==Overview== | ||
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==About this Structure== | ==About this Structure== | ||
| - | 1BEV is a [ | + | 1BEV is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Bovine_enterovirus Bovine enterovirus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BEV OCA]. |
==Reference== | ==Reference== | ||
| - | Implications for viral uncoating from the structure of bovine enterovirus., Smyth M, Tate J, Hoey E, Lyons C, Martin S, Stuart D, Nat Struct Biol. 1995 Mar;2(3):224-31. PMID:[http:// | + | Implications for viral uncoating from the structure of bovine enterovirus., Smyth M, Tate J, Hoey E, Lyons C, Martin S, Stuart D, Nat Struct Biol. 1995 Mar;2(3):224-31. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/7773791 7773791] |
[[Category: Bovine enterovirus]] | [[Category: Bovine enterovirus]] | ||
[[Category: Protein complex]] | [[Category: Protein complex]] | ||
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[[Category: picornavirus]] | [[Category: picornavirus]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 10:10:05 2008'' |
Revision as of 08:10, 20 March 2008
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| , resolution 3.0Å | |||||||
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| Ligands: | and | ||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||
BOVINE ENTEROVIRUS VG-5-27
Overview
We have determined the crystal structure of a bovine enterovirus, revealing that the topologies of the major capsid proteins and the overall architecture of the virion are similar to those of related picornaviruses. The external loops joining beta-strands are truncated and the canyon region is partially filled by an extension of the VP3 G-H loop giving the viral capsid a relatively smooth appearance. These changes may have implications for cell attachment. In spite of these differences the virus maintains a hydrophobic pocket within VP1, occupied by a specific 'pocket factor' which appears to be myristic acid. These observations support the proposal that a kinetic equilibrium exists between occupied and unoccupied pocket states, with occupation inhibiting uncoating.
About this Structure
1BEV is a Protein complex structure of sequences from Bovine enterovirus. Full crystallographic information is available from OCA.
Reference
Implications for viral uncoating from the structure of bovine enterovirus., Smyth M, Tate J, Hoey E, Lyons C, Martin S, Stuart D, Nat Struct Biol. 1995 Mar;2(3):224-31. PMID:7773791
Page seeded by OCA on Thu Mar 20 10:10:05 2008
