1bn9

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[[Image:1bn9.png|left|200px]]
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==RESPONSE ELEMENT OF THE ORPHAN NUCLEAR RECEPTOR REV-ERB BETA==
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<StructureSection load='1bn9' size='340' side='right' caption='[[1bn9]], [[NMR_Ensembles_of_Models | 1 NMR models]]' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1bn9]] is a 2 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BN9 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1BN9 FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1bn9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1bn9 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1bn9 RCSB], [http://www.ebi.ac.uk/pdbsum/1bn9 PDBsum]</span></td></tr>
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<table>
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<div style="background-color:#fffaf0;">
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== Publication Abstract from PubMed ==
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Rev-erb beta is an orphan receptor that binds as a homodimer or as a monomer to DNA. The solution structure of the non-palindromic 15 bp DNA duplex d(TAGAATGTAGGTCAG), the response element of Rev-erb beta for monomeric binding, was determined by 1H and 31P NMR, energy minimization with NMR-derived restraints for distances and NOE back-calculation methods. The refined final structures have the typical overall features of B-type DNA. However, titration of this 15 bp duplex with ReDBD, the DNA binding domain of Rev-erb beta, showed large shifts of imino protons and 31P signals, suggesting major conformational changes.
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{{STRUCTURE_1bn9| PDB=1bn9 | SCENE= }}
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Solution structure of the orphan nuclear receptor rev-erb beta response element by 1H, 31P NMR and molecular simulation*.,Castagne C, Terenzi H, Zakin MM, Delepierre M Biochimie. 2000 Aug;82(8):739-48. PMID:11018291<ref>PMID:11018291</ref>
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===RESPONSE ELEMENT OF THE ORPHAN NUCLEAR RECEPTOR REV-ERB BETA===
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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</div>
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{{ABSTRACT_PUBMED_11018291}}
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== References ==
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<references/>
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==About this Structure==
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__TOC__
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[[1bn9]] is a 2 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BN9 OCA].
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</StructureSection>
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==Reference==
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<ref group="xtra">PMID:011018291</ref><references group="xtra"/>
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[[Category: Castagne, C.]]
[[Category: Castagne, C.]]
[[Category: Delepierre, M.]]
[[Category: Delepierre, M.]]

Revision as of 05:32, 8 June 2014

RESPONSE ELEMENT OF THE ORPHAN NUCLEAR RECEPTOR REV-ERB BETA

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