1bhc
From Proteopedia
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| - | [[Image:1bhc.jpg|left|200px]] | + | [[Image:1bhc.jpg|left|200px]] |
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| - | '''BOVINE PANCREATIC TRYPSIN INHIBITOR CRYSTALLIZED FROM THIOCYANATE''' | + | {{Structure |
| + | |PDB= 1bhc |SIZE=350|CAPTION= <scene name='initialview01'>1bhc</scene>, resolution 2.7Å | ||
| + | |SITE= | ||
| + | |LIGAND= <scene name='pdbligand=SCN:THIOCYANATE ION'>SCN</scene> | ||
| + | |ACTIVITY= | ||
| + | |GENE= | ||
| + | }} | ||
| + | |||
| + | '''BOVINE PANCREATIC TRYPSIN INHIBITOR CRYSTALLIZED FROM THIOCYANATE''' | ||
| + | |||
==Overview== | ==Overview== | ||
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==About this Structure== | ==About this Structure== | ||
| - | 1BHC is a [ | + | 1BHC is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BHC OCA]. |
==Reference== | ==Reference== | ||
| - | The decameric structure of bovine pancreatic trypsin inhibitor (BPTI) crystallized from thiocyanate at 2.7 A resolution., Hamiaux C, Prange T, Ries-Kautt M, Ducruix A, Lafont S, Astier JP, Veesler S, Acta Crystallogr D Biol Crystallogr. 1999 Jan;55(Pt 1):103-13. Epub 1999, Jan 1. PMID:[http:// | + | The decameric structure of bovine pancreatic trypsin inhibitor (BPTI) crystallized from thiocyanate at 2.7 A resolution., Hamiaux C, Prange T, Ries-Kautt M, Ducruix A, Lafont S, Astier JP, Veesler S, Acta Crystallogr D Biol Crystallogr. 1999 Jan;55(Pt 1):103-13. Epub 1999, Jan 1. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/10089400 10089400] |
[[Category: Bos taurus]] | [[Category: Bos taurus]] | ||
[[Category: Single protein]] | [[Category: Single protein]] | ||
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[[Category: trypsin]] | [[Category: trypsin]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 10:11:04 2008'' |
Revision as of 08:11, 20 March 2008
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| , resolution 2.7Å | |||||||
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| Ligands: | |||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||
BOVINE PANCREATIC TRYPSIN INHIBITOR CRYSTALLIZED FROM THIOCYANATE
Overview
The structure of a monoclinic form of bovine pancreatic trypsin inhibitor (BPTI) crystallized from a thiocyanate solution has been determined and refined at 2.7 A resolution. The space group is P21 with a = 71.56, b = 73.83, c = 64.47 A, beta = 93.9 degrees and Z = 20. The ten independent molecules were located by a multi-body molecular-replacement search as developed in the AMoRe program, starting from a single monomer model (PDB code: 6PTI). The molecular arrangement of the subunits is a decamer resulting from the combination of two orthogonal fivefold and twofold non-crystallographic axes. This builds a globular micelle-like particle which minimizes hydrophobic interactions with the solvent. The refinement was conducted with non-crystallographic symmetry constraints up to a final residual of R = 0.20 (Rfree= 0.26). The root-mean-square deviations from ideal geometry were 0.015 A and 1.6 degrees on bond distances and bond angles, respectively. Several sites for thiocyanate ions were analyzed.
About this Structure
1BHC is a Single protein structure of sequence from Bos taurus. Full crystallographic information is available from OCA.
Reference
The decameric structure of bovine pancreatic trypsin inhibitor (BPTI) crystallized from thiocyanate at 2.7 A resolution., Hamiaux C, Prange T, Ries-Kautt M, Ducruix A, Lafont S, Astier JP, Veesler S, Acta Crystallogr D Biol Crystallogr. 1999 Jan;55(Pt 1):103-13. Epub 1999, Jan 1. PMID:10089400
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