1bj8
From Proteopedia
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| - | [[Image:1bj8.gif|left|200px]] | + | [[Image:1bj8.gif|left|200px]] |
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| - | '''THIRD N-TERMINAL DOMAIN OF GP130, NMR, MINIMIZED AVERAGE STRUCTURE''' | + | {{Structure |
| + | |PDB= 1bj8 |SIZE=350|CAPTION= <scene name='initialview01'>1bj8</scene> | ||
| + | |SITE= | ||
| + | |LIGAND= | ||
| + | |ACTIVITY= | ||
| + | |GENE= | ||
| + | }} | ||
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| + | '''THIRD N-TERMINAL DOMAIN OF GP130, NMR, MINIMIZED AVERAGE STRUCTURE''' | ||
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==Overview== | ==Overview== | ||
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==About this Structure== | ==About this Structure== | ||
| - | 1BJ8 is a [ | + | 1BJ8 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BJ8 OCA]. |
==Reference== | ==Reference== | ||
| - | The signal transducer gp130: solution structure of the carboxy-terminal domain of the cytokine receptor homology region., Kernebeck T, Pflanz S, Muller-Newen G, Kurapkat G, Scheek RM, Dijkstra K, Heinrich PC, Wollmer A, Grzesiek S, Grotzinger J, Protein Sci. 1999 Jan;8(1):5-12. PMID:[http:// | + | The signal transducer gp130: solution structure of the carboxy-terminal domain of the cytokine receptor homology region., Kernebeck T, Pflanz S, Muller-Newen G, Kurapkat G, Scheek RM, Dijkstra K, Heinrich PC, Wollmer A, Grzesiek S, Grotzinger J, Protein Sci. 1999 Jan;8(1):5-12. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/10210178 10210178] |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Single protein]] | [[Category: Single protein]] | ||
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[[Category: glycoprotein]] | [[Category: glycoprotein]] | ||
[[Category: receptor]] | [[Category: receptor]] | ||
| - | [[Category: signal transducer of il-6 type | + | [[Category: signal transducer of il-6 type cytokine]] |
[[Category: third n-terminal domain]] | [[Category: third n-terminal domain]] | ||
[[Category: transmembrane]] | [[Category: transmembrane]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 10:11:47 2008'' |
Revision as of 08:11, 20 March 2008
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| Coordinates: | save as pdb, mmCIF, xml | ||||||
THIRD N-TERMINAL DOMAIN OF GP130, NMR, MINIMIZED AVERAGE STRUCTURE
Overview
The transmembrane glycoprotein gp130 is the common signal transducing receptor subunit of the interleukin-6-type cytokines. It is a member of the cytokine-receptor superfamily predicted to consist of six domains in its extracellular part. The second and third domain constitute the cytokine-binding module defined by a set of four conserved cysteines and a WSXWS motif, respectively. The three-dimensional structure of the carboxy-terminal domain of this region was determined by multidimensional NMR. The domain consists of seven beta-strands constituting a fibronectin type III-like topology. The structure reveals that the WSDWS motif of gp130 is part of an extended tryptophan/arginine zipper which modulates the conformation of the CD loop.
About this Structure
1BJ8 is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
The signal transducer gp130: solution structure of the carboxy-terminal domain of the cytokine receptor homology region., Kernebeck T, Pflanz S, Muller-Newen G, Kurapkat G, Scheek RM, Dijkstra K, Heinrich PC, Wollmer A, Grzesiek S, Grotzinger J, Protein Sci. 1999 Jan;8(1):5-12. PMID:10210178
Page seeded by OCA on Thu Mar 20 10:11:47 2008
Categories: Homo sapiens | Single protein | Dijkstra, K. | Grotzinger, J. | Grzesiek, S. | Heinrich, P C. | Kernebeck, T. | Kurapkat, G. | Muller-Newen, G. | Pflanz, S. | Scheek, R M. | Wollmer, A. | Glycoprotein | Receptor | Signal transducer of il-6 type cytokine | Third n-terminal domain | Transmembrane
