200d

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[[Image:200d.png|left|200px]]
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==STABLE LOOP IN THE CRYSTAL STRUCTURE OF THE INTERCALATED FOUR-STRANDED CYTOSINE-RICH METAZOAN TELOMERE==
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<StructureSection load='200d' size='340' side='right' caption='[[200d]], [[Resolution|resolution]] 1.85&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[200d]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=200D OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=200D FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=200d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=200d OCA], [http://www.rcsb.org/pdb/explore.do?structureId=200d RCSB], [http://www.ebi.ac.uk/pdbsum/200d PDBsum]</span></td></tr>
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<table>
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<div style="background-color:#fffaf0;">
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== Publication Abstract from PubMed ==
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In most metazoans, the telomeric cytosine-rich strand repeating sequence is d(TAACCC). The crystal structure of this sequence was solved to 1.9-A resolution. Four strands associate via the cytosine-containing parts to form a four-stranded intercalated structure held together by C.C+ hydrogen bonds. The base-paired strands are parallel to each other, and the two duplexes are intercalated into each other in opposite orientations. One TAA end forms a highly stabilized loop with the 5' thymine Hoogsteen-base-paired to the third adenine. The 5' end of this loop is in close proximity to the 3' end of one of the other intercalated cytosine strands. Instead of being entirely in a DNA duplex, this structure suggests the possibility of an alternative conformation for the cytosine-rich telomere strands.
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{{STRUCTURE_200d| PDB=200d | SCENE= }}
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Stable loop in the crystal structure of the intercalated four-stranded cytosine-rich metazoan telomere.,Kang C, Berger I, Lockshin C, Ratliff R, Moyzis R, Rich A Proc Natl Acad Sci U S A. 1995 Apr 25;92(9):3874-8. PMID:7731999<ref>PMID:7731999</ref>
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===STABLE LOOP IN THE CRYSTAL STRUCTURE OF THE INTERCALATED FOUR-STRANDED CYTOSINE-RICH METAZOAN TELOMERE===
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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</div>
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{{ABSTRACT_PUBMED_7731999}}
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== References ==
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<references/>
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==About this Structure==
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__TOC__
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[[200d]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=200D OCA].
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</StructureSection>
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==Reference==
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<ref group="xtra">PMID:007731999</ref><references group="xtra"/>
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[[Category: Berger, I.]]
[[Category: Berger, I.]]
[[Category: Kang, C.]]
[[Category: Kang, C.]]

Revision as of 06:55, 9 June 2014

STABLE LOOP IN THE CRYSTAL STRUCTURE OF THE INTERCALATED FOUR-STRANDED CYTOSINE-RICH METAZOAN TELOMERE

200d, resolution 1.85Å

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