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2f40

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[[Image:2f40.png|left|200px]]
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==Structure of a Novel Protein from Backbone-Centered NMR Data and NMR-Assisted Structure Prediction==
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<StructureSection load='2f40' size='340' side='right' caption='[[2f40]], [[NMR_Ensembles_of_Models | 10 NMR models]]' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[2f40]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Pyrococcus_furiosus Pyrococcus furiosus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2F40 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2F40 FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2f40 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2f40 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2f40 RCSB], [http://www.ebi.ac.uk/pdbsum/2f40 PDBsum]</span></td></tr>
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<table>
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<div style="background-color:#fffaf0;">
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== Publication Abstract from PubMed ==
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Targeting of proteins for structure determination in structural genomic programs often includes the use of threading and fold recognition methods to exclude proteins belonging to well-populated fold families, but such methods can still fail to recognize preexisting folds. The authors illustrate here a method in which limited amounts of structural data are used to improve an initial homology search and the data are subsequently used to produce a structure by data-constrained refinement of an identified structural template. The data used are primarily NMR-based residual dipolar couplings, but they also include additional chemical shift and backbone-nuclear Overhauser effect data. Using this methodology, a backbone structure was efficiently produced for a 10 kDa protein (PF1455) from Pyrococcus furiosus. Its relationship to existing structures and its probable function are discussed.
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{{STRUCTURE_2f40| PDB=2f40 | SCENE= }}
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Structure determination of a new protein from backbone-centered NMR data and NMR-assisted structure prediction.,Mayer KL, Qu Y, Bansal S, LeBlond PD, Jenney FE Jr, Brereton PS, Adams MW, Xu Y, Prestegard JH Proteins. 2006 Nov 1;65(2):480-9. PMID:16927360<ref>PMID:16927360</ref>
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===Structure of a Novel Protein from Backbone-Centered NMR Data and NMR-Assisted Structure Prediction===
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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</div>
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{{ABSTRACT_PUBMED_16927360}}
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== References ==
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<references/>
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==About this Structure==
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__TOC__
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[[2f40]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Pyrococcus_furiosus Pyrococcus furiosus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2F40 OCA].
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</StructureSection>
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==Reference==
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<ref group="xtra">PMID:016927360</ref><references group="xtra"/>
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[[Category: Pyrococcus furiosus]]
[[Category: Pyrococcus furiosus]]
[[Category: Bansal, S.]]
[[Category: Bansal, S.]]

Revision as of 06:57, 9 June 2014

Structure of a Novel Protein from Backbone-Centered NMR Data and NMR-Assisted Structure Prediction

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