1w9z

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[[Image:1w9z.png|left|200px]]
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==STRUCTURE OF BANNAVIRUS VP9==
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<StructureSection load='1w9z' size='340' side='right' caption='[[1w9z]], [[Resolution|resolution]] 2.56&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1w9z]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Banna_virus Banna virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1W9Z OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1W9Z FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1w9z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1w9z OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1w9z RCSB], [http://www.ebi.ac.uk/pdbsum/1w9z PDBsum]</span></td></tr>
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<table>
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<div style="background-color:#fffaf0;">
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== Publication Abstract from PubMed ==
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Banna virus (BAV: genus Seadornavirus, family Reoviridae) has a double-shelled morphology similar to rotavirus and bluetongue virus. The structure of BAV outer-capsid protein VP9 was determined by X-ray crystallography at 2.6 A resolution, revealing a trimeric molecule, held together by an N-terminal helical bundle, reminiscent of coiled-coil structures found in fusion-active proteins such as HIV gp41. The major domain of VP9 contains stacked beta sheets with marked structural similarities to the receptor binding protein VP8 of rotavirus. Anti-VP9 antibodies neutralize viral infectivity, and, remarkably, pretreatment of cells with trimeric VP9 increased viral infectivity, indicating that VP9 is involved in virus attachment to cell surface and subsequent internalization. Sequence similarities were also detected between BAV VP10 and VP5 portion of rotavirus VP4, suggesting that the receptor binding and internalization apparatus, which is a single gene product activated by proteoloysis in rotavirus, is the product of two separate genome segments in BAV.
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{{STRUCTURE_1w9z| PDB=1w9z | SCENE= }}
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The structure and function of the outer coat protein VP9 of Banna virus.,Mohd Jaafar F, Attoui H, Bahar MW, Siebold C, Sutton G, Mertens PP, De Micco P, Stuart DI, Grimes JM, De Lamballerie X Structure. 2005 Jan;13(1):17-28. PMID:15642258<ref>PMID:15642258</ref>
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===STRUCTURE OF BANNAVIRUS VP9===
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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</div>
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{{ABSTRACT_PUBMED_15642258}}
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== References ==
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<references/>
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==About this Structure==
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__TOC__
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[[1w9z]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Banna_virus Banna virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1W9Z OCA].
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</StructureSection>
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==Reference==
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<ref group="xtra">PMID:015642258</ref><references group="xtra"/>
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[[Category: Banna virus]]
[[Category: Banna virus]]
[[Category: Attoui, H.]]
[[Category: Attoui, H.]]

Revision as of 07:02, 9 June 2014

STRUCTURE OF BANNAVIRUS VP9

1w9z, resolution 2.56Å

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