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354d

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[[Image:354d.png|left|200px]]
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==Structure of loop E FROM E. coli 5S RRNA==
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<StructureSection load='354d' size='340' side='right' caption='[[354d]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[354d]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=354D OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=354D FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene><br>
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<tr><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=G46:2-DEOXY-GUANOSINE-5-MONOTHIOPHOSPHATE'>G46</scene></td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=354d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=354d OCA], [http://www.rcsb.org/pdb/explore.do?structureId=354d RCSB], [http://www.ebi.ac.uk/pdbsum/354d PDBsum]</span></td></tr>
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<table>
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<div style="background-color:#fffaf0;">
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== Publication Abstract from PubMed ==
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Two new RNA structures portray how non-Watson-Crick base pairs and metal ions can produce a unique RNA shape suitable for recognition by proteins. The crystal structures of a 62 nt domain of E. coli 5S ribosomal RNA and a duplex dodecamer encompassing an internal loop E have been determined at 3.0 and 1.5 A, respectively. This loop E region is distorted by three "cross-strand purine stacks" and three novel, water-mediated noncanonical base pairs and stabilized by a four metal ion zipper. These features give its minor groove a unique hydrogen-bonding surface and make the adjacent major groove wide enough to permit recognition by the ribosomal protein L25, which is expected to bind to this surface.
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{{STRUCTURE_354d| PDB=354d | SCENE= }}
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Metals, motifs, and recognition in the crystal structure of a 5S rRNA domain.,Correll CC, Freeborn B, Moore PB, Steitz TA Cell. 1997 Nov 28;91(5):705-12. PMID:9393863<ref>PMID:9393863</ref>
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===Structure of loop E FROM E. coli 5S RRNA===
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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</div>
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{{ABSTRACT_PUBMED_9393863}}
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== References ==
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<references/>
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==About this Structure==
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__TOC__
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[[354d]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=354D OCA].
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</StructureSection>
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==Reference==
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<ref group="xtra">PMID:009393863</ref><references group="xtra"/>
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[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
[[Category: Correll, C C.]]
[[Category: Correll, C C.]]

Revision as of 07:06, 9 June 2014

Structure of loop E FROM E. coli 5S RRNA

354d, resolution 1.50Å

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