1qh2
From Proteopedia
(Difference between revisions)
m (Protected "1qh2" [edit=sysop:move=sysop]) |
|||
| Line 1: | Line 1: | ||
| - | [[ | + | ==CHYMOTRYPSIN INHIBITOR (C2) FROM NICOTIANA ALATA== |
| + | <StructureSection load='1qh2' size='340' side='right' caption='[[1qh2]], [[NMR_Ensembles_of_Models | 1 NMR models]]' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[1qh2]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Nicotiana_alata Nicotiana alata]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QH2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1QH2 FirstGlance]. <br> | ||
| + | </td></tr><tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1qh2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1qh2 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1qh2 RCSB], [http://www.ebi.ac.uk/pdbsum/1qh2 PDBsum]</span></td></tr> | ||
| + | <table> | ||
| + | <div style="background-color:#fffaf0;"> | ||
| + | == Publication Abstract from PubMed == | ||
| + | Female reproductive tissues of the ornamental tobacco amass high levels of serine proteinase inhibitors (PIs) for protection against pests and pathogens. These PIs are produced from a precursor protein composed of six repeats each with a protease reactive site. Here we show that proteolytic processing of the precursor generates five single-chain PIs and a remarkable two-chain inhibitor formed by disulfide-bond linkage of N- and C-terminal peptide fragments. Surprisingly, PI precursors adopt this circular structure regardless of the number of inhibitor domains, suggesting this bracelet-like conformation is characteristic of the widespread potato inhibitor II (Pot II) protein family. | ||
| - | + | A novel two-chain proteinase inhibitor generated by circularization of a multidomain precursor protein.,Lee MC, Scanlon MJ, Craik DJ, Anderson MA Nat Struct Biol. 1999 Jun;6(6):526-30. PMID:10360353<ref>PMID:10360353</ref> | |
| - | + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | |
| - | + | </div> | |
| - | + | == References == | |
| - | + | <references/> | |
| - | + | __TOC__ | |
| - | + | </StructureSection> | |
| - | + | ||
| - | == | + | |
| - | < | + | |
[[Category: Nicotiana alata]] | [[Category: Nicotiana alata]] | ||
[[Category: Anderson, M A.]] | [[Category: Anderson, M A.]] | ||
Revision as of 07:09, 9 June 2014
CHYMOTRYPSIN INHIBITOR (C2) FROM NICOTIANA ALATA
| |||||||||||
