4akd
From Proteopedia
(Difference between revisions)
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| - | [[ | + | ==High resolution structure of Mannose Binding lectin from Champedak (CMB)== |
| + | <StructureSection load='4akd' size='340' side='right' caption='[[4akd]], [[Resolution|resolution]] 2.10Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[4akd]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Artocarpus_integer Artocarpus integer]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4AKD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4AKD FirstGlance]. <br> | ||
| + | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CD:CADMIUM+ION'>CD</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene><br> | ||
| + | <tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4ak4|4ak4]], [[4akb|4akb]], [[4akc|4akc]]</td></tr> | ||
| + | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4akd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4akd OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4akd RCSB], [http://www.ebi.ac.uk/pdbsum/4akd PDBsum]</span></td></tr> | ||
| + | <table> | ||
| + | <div style="background-color:#fffaf0;"> | ||
| + | == Publication Abstract from PubMed == | ||
| + | Mannose-binding lectin from champedak (Artocarpus integer) is a homotetramer with a single-monomer molecular weight of 16 800 Da. Previous work has shown it to bind IgE and IgM, as well as being a mitogen of T cells in humans. Champedak mannose-binding lectin has successfully been used to detect altered glycosylation states of serum proteins. The protein was crystallized at 293 K in space group P2(1)2(1)2(1) (unit-cell parameters a = 76.89, b = 86.22, c = 95.37 A) and the crystals diffracted to 2.0 A resolution. | ||
| - | + | Crystallization and initial X-ray diffraction analysis of a mannose-binding lectin from champedak.,Gabrielsen M, Abdul-Rahman PS, Isaacs NW, Hashim OH, Cogdell RJ Acta Crystallogr Sect F Struct Biol Cryst Commun. 2010 May 1;66(Pt 5):592-4. doi:, 10.1107/S1744309110011760. Epub 2010 Apr 30. PMID:20445267<ref>PMID:20445267</ref> | |
| - | + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | |
| - | + | </div> | |
| - | + | == References == | |
| - | + | <references/> | |
| - | == | + | __TOC__ |
| - | + | </StructureSection> | |
[[Category: Artocarpus integer]] | [[Category: Artocarpus integer]] | ||
[[Category: Abdul-Rahman, P S.]] | [[Category: Abdul-Rahman, P S.]] | ||
Revision as of 06:30, 11 June 2014
High resolution structure of Mannose Binding lectin from Champedak (CMB)
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