4n8r
From Proteopedia
(Difference between revisions)
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<StructureSection load='4n8r' size='340' side='right' caption='[[4n8r]], [[Resolution|resolution]] 2.03Å' scene=''> | <StructureSection load='4n8r' size='340' side='right' caption='[[4n8r]], [[Resolution|resolution]] 2.03Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[4n8r]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4N8R OCA]. <br> | + | <table><tr><td colspan='2'>[[4n8r]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4N8R OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4N8R FirstGlance]. <br> |
</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=K08:5-(2-{(1Z)-2-METHYL-1-[4-(PROPAN-2-YL)BENZYLIDENE]-1H-INDEN-3-YL}ETHYL)-1H-TETRAZOLE'>K08</scene><br> | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=K08:5-(2-{(1Z)-2-METHYL-1-[4-(PROPAN-2-YL)BENZYLIDENE]-1H-INDEN-3-YL}ETHYL)-1H-TETRAZOLE'>K08</scene><br> | ||
<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4n5g|4n5g]]</td></tr> | <tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4n5g|4n5g]]</td></tr> | ||
| - | <tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucokinase Glucokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.2 2.7.1.2] </span></td></tr> | ||
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4n8r FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4n8r OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4n8r RCSB], [http://www.ebi.ac.uk/pdbsum/4n8r PDBsum]</span></td></tr> | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4n8r FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4n8r OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4n8r RCSB], [http://www.ebi.ac.uk/pdbsum/4n8r PDBsum]</span></td></tr> | ||
<table> | <table> | ||
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Sulindac-Derived RXRalpha Modulators Inhibit Cancer Cell Growth by Binding to a Novel Site.,Chen L, Wang ZG, Aleshin AE, Chen F, Chen J, Jiang F, Alitongbieke G, Zeng Z, Ma Y, Huang M, Zhou H, Cadwell G, Zheng JF, Huang PQ, Liddington RC, Zhang XK, Su Y Chem Biol. 2014 Apr 2. pii: S1074-5521(14)00077-5. doi:, 10.1016/j.chembiol.2014.02.017. PMID:24704507<ref>PMID:24704507</ref> | Sulindac-Derived RXRalpha Modulators Inhibit Cancer Cell Growth by Binding to a Novel Site.,Chen L, Wang ZG, Aleshin AE, Chen F, Chen J, Jiang F, Alitongbieke G, Zeng Z, Ma Y, Huang M, Zhou H, Cadwell G, Zheng JF, Huang PQ, Liddington RC, Zhang XK, Su Y Chem Biol. 2014 Apr 2. pii: S1074-5521(14)00077-5. doi:, 10.1016/j.chembiol.2014.02.017. PMID:24704507<ref>PMID:24704507</ref> | ||
| - | From | + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> |
</div> | </div> | ||
== References == | == References == | ||
Revision as of 06:47, 11 June 2014
Crystal structure of RXRa LBD complexed with a synthetic modulator K-8008
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