4euw

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[[Image:4euw.png|left|200px]]
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==Crystal structure of a HMG domain of transcription factor SOX-9 bound to DNA (SOX-9/DNA) from Homo sapiens at 2.77 A resolution==
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<StructureSection load='4euw' size='340' side='right' caption='[[4euw]], [[Resolution|resolution]] 2.77&Aring;' scene=''>
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{{STRUCTURE_4euw| PDB=4euw | SCENE= }}
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4euw]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4EUW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4EUW FirstGlance]. <br>
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===Crystal structure of a HMG domain of transcription factor SOX-9 bound to DNA (SOX-9/DNA) from Homo sapiens at 2.77 A resolution===
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</td></tr><tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">SGT82680, SOX9 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4euw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4euw OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4euw RCSB], [http://www.ebi.ac.uk/pdbsum/4euw PDBsum]</span></td></tr>
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<table>
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==About this Structure==
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== Disease ==
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[[4euw]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4EUW OCA].
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[[http://www.uniprot.org/uniprot/SOX9_HUMAN SOX9_HUMAN]] Campomelic dysplasia;46,XX testicular disorder of sex development;46,XX ovotesticular disorder of sex development. The disease is caused by mutations affecting the gene represented in this entry. The disease is caused by mutations affecting the gene represented in this entry.
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== Function ==
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[[http://www.uniprot.org/uniprot/SOX9_HUMAN SOX9_HUMAN]] Plays an important role in the normal skeletal development. May regulate the expression of other genes involved in chondrogenesis by acting as a transcription factor for these genes.
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__TOC__
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</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: JCSG, Joint Center for Structural Genomics.]]
[[Category: JCSG, Joint Center for Structural Genomics.]]

Revision as of 09:09, 11 June 2014

Crystal structure of a HMG domain of transcription factor SOX-9 bound to DNA (SOX-9/DNA) from Homo sapiens at 2.77 A resolution

4euw, resolution 2.77Å

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