User:John S. de Banzie/Sandbox 2
From Proteopedia
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==RNA Stem and Loop Structure== | ==RNA Stem and Loop Structure== | ||
<StructureSection load='2qh2' size='400' side='right' caption='RNA hairpin loop from human telomerase RNA, [[2qh2]]' scene='59/590622/2qh2stick/1'> | <StructureSection load='2qh2' size='400' side='right' caption='RNA hairpin loop from human telomerase RNA, [[2qh2]]' scene='59/590622/2qh2stick/1'> | ||
| - | Intramolecular hydrogen bonding in RNA molecules results in the formation of stem and loop (also known as hairpin loop) structures. | + | Intramolecular hydrogen bonding in RNA molecules results in the formation of stem and loop (also known as hairpin loop) structures. |
| - | Note that the | + | Note that the RNA forms a double stranded <scene name='59/590622/2qh2stickends/1'>antiparallel</scene> right-handed helix with <scene name='59/590622/2qh2spacefill/1'>major and minor grooves</scene>. Note also that the structure is not the same as that of [[DNA]]. |
| - | Note the <scene name='59/590622/2qh2bases/ | + | The RNA shown is 24 nucleotides long. Nucleotides 1 through 8 and 17 through 24 form a stem and nucleotides 9 through 16 form a loop. Note the <scene name='59/590622/2qh2bases/2'>complementary base pairing</scene> in the stem (A: red, C: green, G: orange, T: blue) and the unpaired bases in the loop (white). |
| - | (The stem and loop structure shown is part of the RNA in human telomerase. Telomerase protects chromosomes by restoring DNA that is lost from the ends during DNA replication. The RNA is used as a template and the enzyme is thus an internally templated RNA-dependant DNA polymerase.) | + | (The stem and loop structure shown is part of the RNA in human telomerase. Telomerase protects chromosomes by restoring DNA that is lost from the ends during DNA replication. The RNA is used as a template and the enzyme is thus an internally-templated RNA-dependant DNA polymerase.) |
</StructureSection> | </StructureSection> | ||
== References == | == References == | ||
<references/> | <references/> | ||
Revision as of 16:02, 13 June 2014
RNA Stem and Loop Structure
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