2ce4

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[[Category: radiation resistance]]
[[Category: radiation resistance]]
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Revision as of 15:00, 30 October 2007


2ce4, resolution 2.20Å

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MANGANESE SUPEROXIDE DISMUTASE (MN-SOD) FROM DEINOCOCCUS RADIODURANS

Overview

The structure of the manganese superoxide dismutase (Mn-SOD; DR1279) from, Deinococcus radiodurans has been determined in two different crystal, forms. Both crystal forms are monoclinic with space group P2(1). Form I, has unit-cell parameters a = 44.28, b = 83.21, c = 59.52 angstroms, beta =, 110.18 degrees and contains a homodimer in the asymmetric unit, with, structure refinement (R = 16.8%, R(free) = 23.6%) carried out using data, to d(min) = 2.2 angstroms. Form II has unit-cell parameters a = 43.57, b =, 87.10, c = 116.42 angstroms, beta = 92.1 degrees and an asymmetric unit, containing two Mn-SOD homodimers; structure refinement was effected to a, resolution of 2.0 angstroms (R = 17.2%, R(free) = 22.3%). The resulting, structures are compared with that of Mn-SOD from Escherichia ... [(full description)]

About this Structure

2CE4 is a [Single protein] structure of sequence from [Deinococcus radiodurans] with MN as [ligand]. Active as [Superoxide dismutase], with EC number [1.15.1.1]. Structure known Active Site: AC1. Full crystallographic information is available from [OCA].

Reference

Structure of the manganese superoxide dismutase from Deinococcus radiodurans in two crystal forms., Dennis RJ, Micossi E, McCarthy J, Moe E, Gordon EJ, Kozielski-Stuhrmann S, Leonard GA, McSweeney S, Acta Crystallograph Sect F Struct Biol Cryst Commun. 2006 Apr 1;62(Pt, 4):325-9. Epub 2006 Mar 25. PMID:16582477

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