4n8x

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{{STRUCTURE_4n8x| PDB=4n8x | SCENE= }}
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==The structure of Nostoc sp. PCC 7120 CcmL==
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===The structure of Nostoc sp. PCC 7120 CcmL===
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<StructureSection load='4n8x' size='340' side='right' caption='[[4n8x]], [[Resolution|resolution]] 1.93&Aring;' scene=''>
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{{ABSTRACT_PUBMED_24504539}}
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4n8x]] is a 30 chain structure with sequence from [http://en.wikipedia.org/wiki/Anabaena_7120 Anabaena 7120]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4N8X OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4N8X FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene><br>
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<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4n8f|4n8f]]</td></tr>
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<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ccmL ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=103690 Anabaena 7120])</td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4n8x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4n8x OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4n8x RCSB], [http://www.ebi.ac.uk/pdbsum/4n8x PDBsum]</span></td></tr>
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<table>
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<div style="background-color:#fffaf0;">
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== Publication Abstract from PubMed ==
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CcmL is a small, pentameric protein that is argued to fill the vertices of beta-carboxysomal shell. Here we report the structures of two CcmL orthologs, those from Nostoc sp. PCC 7120 and Thermosynechococcus elongatus BP-1. These structures broadly resemble those previously reported for other strains. However, the Nostoc CcmL structure shows an interesting pattern of behavior where two loops that map to the base of the pentamer adopt either an out or in conformation, with a consistent (over six pentamers) out-in-out-in-in pattern of protomers. The pentamers in this structure are also consistently organized into a back-to-back decamer, though evidence suggests that this is likely not present in solution. Forster resonance energy transfer experiments were able to show a weak interaction between CcmL and CcmK2 when CcmK2 was present at &gt;100 muM. Since CcmK2 forms defined bodies with approximately 200 nm diameter at this concentration, this would support the idea that CcmL can only interact with CcmK2 at rare defect points in the growing shell.
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==About this Structure==
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Interactions and structural variability of beta-carboxysomal shell protein CcmL.,Keeling TJ, Samborska B, Demers RW, Kimber MS Photosynth Res. 2014 Feb 7. PMID:24504539<ref>PMID:24504539</ref>
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[[4n8x]] is a 30 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4N8X OCA].
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==Reference==
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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<ref group="xtra">PMID:024504539</ref><references group="xtra"/><references/>
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</div>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Anabaena 7120]]
[[Category: Keeling, T J.]]
[[Category: Keeling, T J.]]
[[Category: Kimber, M S.]]
[[Category: Kimber, M S.]]

Revision as of 09:22, 16 July 2014

The structure of Nostoc sp. PCC 7120 CcmL

4n8x, resolution 1.93Å

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