4npv

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'''Unreleased structure'''
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==Crystal structure of human PDE1B bound to inhibitor 7A (6,7,8-trimethoxy-N-(pentan-3-yl)quinazolin-4-amine)==
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<StructureSection load='4npv' size='340' side='right' caption='[[4npv]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
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The entry 4npv is ON HOLD until Paper Publication
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4npv]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4NPV OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4NPV FirstGlance]. <br>
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Authors: Pandit, J., Evdomikov, A., Mansour, M., Simons, S.
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=0NK:6,7,8-TRIMETHOXY-N-(PENTAN-3-YL)QUINAZOLIN-4-AMINE'>0NK</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene><br>
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<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4npw|4npw]]</td></tr>
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Description:
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<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/3',5'-cyclic-nucleotide_phosphodiesterase 3',5'-cyclic-nucleotide phosphodiesterase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.4.17 3.1.4.17] </span></td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4npv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4npv OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4npv RCSB], [http://www.ebi.ac.uk/pdbsum/4npv PDBsum]</span></td></tr>
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<table>
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__TOC__
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</StructureSection>
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[[Category: 3',5'-cyclic-nucleotide phosphodiesterase]]
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[[Category: Evdomikov, A.]]
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[[Category: Mansour, M.]]
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[[Category: Pandit, J.]]
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[[Category: Simons, S.]]
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[[Category: Hydrolase]]
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[[Category: Hydrolase-hydrolase inhibitor complex]]

Revision as of 10:29, 16 July 2014

Crystal structure of human PDE1B bound to inhibitor 7A (6,7,8-trimethoxy-N-(pentan-3-yl)quinazolin-4-amine)

4npv, resolution 2.40Å

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