4qgi

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'''Unreleased structure'''
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==X-ray crystal structure of HIV-1 protease variant G48T/L89M in complex with Saquinavir==
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<StructureSection load='4qgi' size='340' side='right' caption='[[4qgi]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
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The entry 4qgi is ON HOLD
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4qgi]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4QGI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4QGI FirstGlance]. <br>
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Authors: Mahon, B.P., McKenna, R., Goldfarb, N.
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=ROC:(2S)-N-[(2S,3R)-4-[(2S,3S,4AS,8AS)-3-(TERT-BUTYLCARBAMOYL)-3,4,4A,5,6,7,8,8A-OCTAHYDRO-1H-ISOQUINOLIN-2-YL]-3-HYDROXY-1-PHENYL-BUTAN-2-YL]-2-(QUINOLIN-2-YLCARBONYLAMINO)BUTANEDIAMIDE'>ROC</scene><br>
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<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/HIV-1_retropepsin HIV-1 retropepsin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.23.16 3.4.23.16] </span></td></tr>
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Description: X-ray crystal structure of HIV-1 protease variant G48T/L89M in complex with Saquinavir
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4qgi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4qgi OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4qgi RCSB], [http://www.ebi.ac.uk/pdbsum/4qgi PDBsum]</span></td></tr>
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<table>
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__TOC__
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</StructureSection>
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[[Category: HIV-1 retropepsin]]
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[[Category: Goldfarb, N.]]
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[[Category: Mahon, B P.]]
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[[Category: McKenna, R.]]
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[[Category: Hiv protease]]
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[[Category: Hydrolase-hydrolase inhibitor complex]]
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[[Category: Saquinavir]]

Revision as of 10:33, 16 July 2014

X-ray crystal structure of HIV-1 protease variant G48T/L89M in complex with Saquinavir

4qgi, resolution 1.90Å

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