4fs4
From Proteopedia
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| - | [[ | + | ==Structure of BACE Bound to (S)-4-(3'-methoxy-[1,1'-biphenyl]-3-yl)-1,4-dimethyl-6-oxotetrahydropyrimidin-2(1H)-iminium== |
| + | <StructureSection load='4fs4' size='340' side='right' caption='[[4fs4]], [[Resolution|resolution]] 1.74Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[4fs4]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4FS4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4FS4 FirstGlance]. <br> | ||
| + | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=H24:(6S)-2-AMINO-6-(3-METHOXYBIPHENYL-3-YL)-3,6-DIMETHYL-5,6-DIHYDROPYRIMIDIN-4(3H)-ONE'>H24</scene>, <scene name='pdbligand=TLA:L(+)-TARTARIC+ACID'>TLA</scene><br> | ||
| + | <tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">BACE, BACE1, KIAA1149 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> | ||
| + | <tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Memapsin_2 Memapsin 2], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.23.46 3.4.23.46] </span></td></tr> | ||
| + | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4fs4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4fs4 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4fs4 RCSB], [http://www.ebi.ac.uk/pdbsum/4fs4 PDBsum]</span></td></tr> | ||
| + | <table> | ||
| - | + | ==See Also== | |
| - | + | *[[Beta secretase|Beta secretase]] | |
| - | == | + | __TOC__ |
| - | + | </StructureSection> | |
| - | + | [[Category: Human]] | |
| - | + | ||
| - | [[ | + | |
[[Category: Memapsin 2]] | [[Category: Memapsin 2]] | ||
[[Category: Stamford, A.]] | [[Category: Stamford, A.]] | ||
Revision as of 10:45, 16 July 2014
Structure of BACE Bound to (S)-4-(3'-methoxy-[1,1'-biphenyl]-3-yl)-1,4-dimethyl-6-oxotetrahydropyrimidin-2(1H)-iminium
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