Human rhinovirus

Function

Human rhinovirus (HRV) are RNA viruses. The HRV capsid is composed of 4 proteins: VP1, VP2, VP3 and VP4. The capsid structure is that of a icosahedron with 60 copies of each of its viral proteins.

Disease

HRV are responsible for the majority of cold-like illnesses.

Relevance

Structural highlights

3D structures of human rhinovirus

Updated on 20-July-2014

Human rhinovirus 14

4rhv, 1rmu – HRV14 VP1+VP2+VP3+VP4
1r08, 2r04, 2r06, 2r07, 2rm2, 2rmu, 2rr1, 2rs1, 2rs3, 2rs5, 1r09, 1hri, 2hwb, 2hwc, 1hrv, 1na1, 1ncq – HRV14 VP1+VP2+VP3+VP4 + antiviral agent
1ruc, 1rud, 1rue, 1ruf, 1rug, 1ruh, 1rui, 1ruj, 1vrh – HRV14 VP1+VP2+VP3+VP4 (mutant) + antiviral agent
1rvf – HRV14 VP1+VP2+VP3+VP4 + antibody
1d3i – HRV14 VP1+VP2+VP3+VP4 + intercellular adhesion molecule – Cryo-EM
1k5m – HRV14 VP1+VP2/V3 of Gp120+VP3+VP4

Human rhinovirus 2

1fpn – HRV2 VP1+VP2+VP3+VP4
1v9u, 3dpr – HRV2 VP1+VP2+VP3+VP4 + LDL-receptor class A3
3vdd – HRV2 VP1+VP2+VP3+VP4 + antiviral agent

References