Function
NADPH dehydrogenase or old yellow enzyme (OYE) catalyzes the conversion of NADPH, H+ and acceptor to NADP+ and reduced acceptor. The acceptor is a quinone. OYE is a flavoenzyme with two cofactors: FAD and FMN.
Disease
Relevance
Structural highlights
3D Structures of NADPH dehydrogenase
Updated on 22-July-2014
1oyc, 1oya – yOYE + FMN - yeast
1k02, 4h6k, 4k7y – yOYE (mutant) + FMN
1bwk, 1bwl – OYE (mutant) + FMN - Candida albicans
NADPH dehydrogenase complexes
1oyb – yOYE + FMN + p-hydroxybenzaldehyde
1k03 – yOYE (mutant) + FMN + p-hydroxybenzaldehyde
3rnd – yOYE (mutant) + FMN + hydroxymethyl cyclopent-2-en-one
4gbu, 4gxm, 4k8e – yOYE (mutant) + FMN + methyl propenyl phenol
4ge8, 3txz, 4gwe, 4h4i, 4k7v, 4k8e – yOYE (mutant) + FMN + carvone
3tx9 – yOYE + FMN + hydroxymethyl cyclopent-2-en-one
References
