4j1n
From Proteopedia
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| - | ''' | + | ==Crystal structures of FabI from F. tularensis in complex with novel inhibitors based on the benzimidazole scaffold== |
| - | + | <StructureSection load='4j1n' size='340' side='right' caption='[[4j1n]], [[Resolution|resolution]] 2.45Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[4j1n]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4J1N OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4J1N FirstGlance]. <br> | |
| - | + | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=1JN:1-(4-METHOXY-3-METHYLBENZYL)-1,5,6,7-TETRAHYDROINDENO[5,6-D]IMIDAZOLE'>1JN</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene><br> | |
| - | + | <tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3uic|3uic]], [[4j3f|4j3f]], [[4j4t|4j4t]]</td></tr> | |
| - | + | <tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Enoyl-[acyl-carrier-protein]_reductase_(NADH) Enoyl-[acyl-carrier-protein] reductase (NADH)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.3.1.9 1.3.1.9] </span></td></tr> | |
| + | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4j1n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4j1n OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4j1n RCSB], [http://www.ebi.ac.uk/pdbsum/4j1n PDBsum]</span></td></tr> | ||
| + | <table> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Boci, T.]] | ||
| + | [[Category: Brubaker, L.]] | ||
| + | [[Category: Johnson, M E.]] | ||
| + | [[Category: Mehboob, S.]] | ||
| + | [[Category: Santarsiero, B D.]] | ||
| + | [[Category: Nadh]] | ||
| + | [[Category: Oxidoreductase-oxidoreductase inhibitor complex]] | ||
| + | [[Category: Reductase]] | ||
| + | [[Category: Reduction]] | ||
| + | [[Category: Rossman fold]] | ||
Revision as of 08:05, 23 July 2014
Crystal structures of FabI from F. tularensis in complex with novel inhibitors based on the benzimidazole scaffold
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