Serpin
From Proteopedia
(Difference between revisions)
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<StructureSection load='3ndd' size='400' side='right' caption='Structure of cleaved human serpin A1. Residues 46-382 (grey), residues 383-418 (green). (PDB entry [[3ndd]])' scene=''> | <StructureSection load='3ndd' size='400' side='right' caption='Structure of cleaved human serpin A1. Residues 46-382 (grey), residues 383-418 (green). (PDB entry [[3ndd]])' scene=''> | ||
| - | '''Serpin or serine protease inhibitor''' (Ser) are protease inhibitors. | + | '''Serpin or serine protease inhibitor''' (Ser) are protease inhibitors.<br /> |
| + | * Ser E1 is antithrombin. <br /> | ||
| + | * Ser C1 is antithrombin.<br /> | ||
| + | * Ser A5 is protein C inhibitor.<br /> | ||
| + | * Ser A6 is a cortisol-binding globulin. <br /> | ||
| + | * Ser A8 is angiotensinogen. <br /> | ||
| + | * Ser A7 is a thyroxine-binding globulin.<br /> | ||
| + | * Ser B1 is leukocyte elastase inhibitor.<br /> | ||
| + | * Ser B3 is squamos cell carcinoma antigen 1. <br /> | ||
| + | * Ser B5 is Maspin.<br /> | ||
| + | * Ser I1 is neuroserpin. <br /> | ||
| + | * Ser A10 is protein Z-related protease inhibitor. <br /> | ||
| + | * Ser A1 is alpha-1 antitrypsin. <br /> | ||
| + | * Ser A3 is α 1-antichymotrypsin.<br /> | ||
| + | * Ser E1 is plasminogen activator inhibitor 1. | ||
==3D structures of serpin== | ==3D structures of serpin== | ||
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[[Alpha-1-antitrypsin]] | [[Alpha-1-antitrypsin]] | ||
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| + | ===Ser A3 (α 1-antichymotrypsin)=== | ||
| + | |||
| + | [[2ach]], [[1as4]], [[3caa]] – hSer-A3<br /> | ||
| + | [[4caa]], [[1qmn]], [[3dlw]] – hSer-A3 (mutant)<br /> | ||
| + | [[1yxa]] – Ser-A3N - mouse<br /> | ||
===Ser A5=== | ===Ser A5=== | ||
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[[4if8]] – hSer-A12<br /> | [[4if8]] – hSer-A12<br /> | ||
| + | |||
| + | ===Ser B1 (leukocyte elastase inhibitor)=== | ||
| + | |||
| + | [[1hle]] – Ser-B1 – horse <br /> | ||
| + | [[4ga7]] – hSer-B1 (mutant) <br /> | ||
===Ser B3=== | ===Ser B3=== | ||
[[2zv6]] – hSer-B3 | [[2zv6]] – hSer-B3 | ||
| + | |||
| + | ===Ser B5 (Maspin)=== | ||
| + | |||
| + | [[1xqg]], [[1wz9]], [[1xu8]] - hSer-B5<br /> | ||
| + | [[1xqj]] – hSer-B5 (mutant) <br /> | ||
===Ser C1=== | ===Ser C1=== | ||
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[[3pzf]] – Ser-2 – malaria mosquito | [[3pzf]] – Ser-2 – malaria mosquito | ||
| - | ===Maspin=== | ||
| - | |||
| - | [[1xqg]], [[1xqj]], [[1wz9]], [[1xu8]] - hMapsin | ||
Revision as of 08:03, 28 July 2014
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