4o91

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'''Unreleased structure'''
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==Crystal Structure of type II inhibitor NG25 bound to TAK1-TAB1==
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<StructureSection load='4o91' size='340' side='right' caption='[[4o91]], [[Resolution|resolution]] 2.39&Aring;' scene=''>
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The entry 4o91 is ON HOLD until Paper Publication
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4o91]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4O91 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4O91 FirstGlance]. <br>
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Authors: Gurbani, D., Hunter, J.C., Tan, L., Westover, K.D.
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NG2:N-{4-[(4-ETHYLPIPERAZIN-1-YL)METHYL]-3-(TRIFLUOROMETHYL)PHENYL}-4-METHYL-3-(1H-PYRROLO[2,3-B]PYRIDIN-4-YLOXY)BENZAMIDE'>NG2</scene><br>
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<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Mitogen-activated_protein_kinase_kinase_kinase Mitogen-activated protein kinase kinase kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.25 2.7.11.25] </span></td></tr>
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Description: Crystal Structure of type II inhibitor NG25 bound to TAK1-TAB1
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4o91 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4o91 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4o91 RCSB], [http://www.ebi.ac.uk/pdbsum/4o91 PDBsum]</span></td></tr>
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<table>
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__TOC__
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</StructureSection>
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[[Category: Mitogen-activated protein kinase kinase kinase]]
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[[Category: Gurbani, D.]]
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[[Category: Hunter, J C.]]
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[[Category: Tan, L.]]
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[[Category: Westover, K D.]]
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[[Category: Mitogen-activated protein kinase kinase kinase 7]]
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[[Category: Serine/threonine kinase which acts as an essential component of the map kinase signal transduction pathway]]
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[[Category: Tgf-beta-activated kinase 1 and map3k7-binding protein 1]]
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[[Category: Tgf-beta-activated kinase 1 and map3k7-binding protein 1 chimera]]
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[[Category: Transferase-transferase inhibitor complex]]

Revision as of 07:48, 30 July 2014

Crystal Structure of type II inhibitor NG25 bound to TAK1-TAB1

4o91, resolution 2.39Å

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