Alpha-glucosidase

Function

Alpha glucosidase (AGS) or maltase beaks down the 1,4-α bonds in starch or disaccharides to produce glucose. Maltase breaks down maltose. Isomaltase breaks the 1,6 bond.

Disease

Relevance

Structural highlights

3D structures of α-glucosidase

Updated on 05-August-2014

2g3m – SsAGS – Sulfolobus solfataricus

2ze0 – AGS – Geobacillus
3w38 – bAGS - beet

Maltase complex

1vjt – TmAGS + NAD – Thermotoga maritima
1obb – TmAGS + NAD + maltose
2g3n – SsAGS + octylglucoside
3w37 – bAGS + acarbose
3wel, 3wem, 3wen, 3weo – bAGS + acarviosyl-maltooligosaccharide

Isomaltase

3a47, 3aj7 – yAGS – yeast
3a4a, 3axh – yAGS + glucose
3axi – yAGS (mutant) + glucose<br /

References