Sandbox bcce6
From Proteopedia
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The Leucine Zipper is a protein structural motif consisting of two alpha helices coiled around each other. The crystal structure shown here (PDB ID:2ZTA) is a small part of a much larger protein from yeast called GCN4. | The Leucine Zipper is a protein structural motif consisting of two alpha helices coiled around each other. The crystal structure shown here (PDB ID:2ZTA) is a small part of a much larger protein from yeast called GCN4. | ||
| - | The two <scene name='59/596443/Backbone_overview/1'>backbones</scene> together make a left handed superhelix. The amino acids between the two helices are <scene name='59/596443/Nonpolar/1'>nonpolar (valine, leucine, and isoleucine)</scene>, although there is one pair of asparagines that hydrogen bond at the center. The many <scene name='59/596443/Leucines_ball_and_stick/1'>leucines</scene> obviously give the name for this protein motif | + | The two <scene name='59/596443/Backbone_overview/1'>backbones</scene> together make a left handed superhelix. The amino acids between the two helices are <scene name='59/596443/Nonpolar/1'>nonpolar (valine, leucine, and isoleucine)</scene>, although there is one pair of asparagines that hydrogen bond at the center. The many <scene name='59/596443/Leucines_ball_and_stick/1'>leucines</scene> obviously give the name for this protein motif. |
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== Model == | == Model == | ||
| - | [[Image:LeucineZipperMolecularOrigami.png|thumb|alt= | + | [[Image:LeucineZipperMolecularOrigami.png|thumb|alt=Paper model of 2zta|link=[http://molecularorigami.com]|Paper model of 2ZTA]] This paper model of the leucine zipper can be made from a PDF available from MolecularOrigami.com. The model is challenging to build (skill level 4 out of 5) because it requires careful control of the curvature of each helix. Hydrophobic side chains between the helices are represented by pieces of paper that are glued to the peptide planes. Several of these models can be attached in sequence to make a representation of the long fibrous portion of myosin. |
== Function == | == Function == | ||
Revision as of 15:36, 6 August 2014
Leucine Zipper
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