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Nitrile hydratase

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== Function ==
== Function ==
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'''Nitrile hydratase''' (NH) catalyze the hydration of nitriles to amides. NH contains Fe or Co in its active site. NH consists of two subunits: α and β and exists as dimer or tetramer with one metal ion bound per dimer.
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'''Nitrile hydratase''' (NH) catalyze the hydration of nitriles to amides. NH contains Fe or Co ion in its active site. NH consists of two subunits: α and β and exists as dimer or tetramer with one metal ion bound per dimer.
== Disease ==
== Disease ==

Revision as of 06:49, 13 August 2014

Structure of nitrile hydratase α (grey),β (green) subunits complex with Fe+3 ion (orange) and trimethylacetonitrile (PDB code 3a8o).

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Michal Harel, Alexander Berchansky

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