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1dir

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[[Image:1dir.gif|left|200px]]<br /><applet load="1dir" size="350" color="white" frame="true" align="right" spinBox="true"
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[[Image:1dir.gif|left|200px]]
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caption="1dir, resolution 2.60&Aring;" />
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'''CRYSTAL STRUCTURE OF A MONOCLINIC FORM OF DIHYDROPTERIDINE REDUCTASE FROM RAT LIVER'''<br />
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{{Structure
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|PDB= 1dir |SIZE=350|CAPTION= <scene name='initialview01'>1dir</scene>, resolution 2.60&Aring;
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|SITE=
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|LIGAND= <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene>
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|ACTIVITY= [http://en.wikipedia.org/wiki/6,7-dihydropteridine_reductase 6,7-dihydropteridine reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.5.1.34 1.5.1.34]
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|GENE=
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}}
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'''CRYSTAL STRUCTURE OF A MONOCLINIC FORM OF DIHYDROPTERIDINE REDUCTASE FROM RAT LIVER'''
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==Overview==
==Overview==
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==About this Structure==
==About this Structure==
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1DIR is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus] with <scene name='pdbligand=NAD:'>NAD</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/6,7-dihydropteridine_reductase 6,7-dihydropteridine reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.5.1.34 1.5.1.34] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DIR OCA].
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1DIR is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DIR OCA].
==Reference==
==Reference==
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Crystal structure of a monoclinic form of dihydropteridine reductase from rat liver., Su Y, Skinner MM, Xuong NH, Matthews DA, Whiteley JM, Varughese KI, Acta Crystallogr D Biol Crystallogr. 1994 Nov 1;50(Pt 6):884-8. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=15299357 15299357]
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Crystal structure of a monoclinic form of dihydropteridine reductase from rat liver., Su Y, Skinner MM, Xuong NH, Matthews DA, Whiteley JM, Varughese KI, Acta Crystallogr D Biol Crystallogr. 1994 Nov 1;50(Pt 6):884-8. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15299357 15299357]
[[Category: 6,7-dihydropteridine reductase]]
[[Category: 6,7-dihydropteridine reductase]]
[[Category: Rattus norvegicus]]
[[Category: Rattus norvegicus]]
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[[Category: oxidoreductase(acting on nadh or nadph)]]
[[Category: oxidoreductase(acting on nadh or nadph)]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 12:16:57 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 10:39:03 2008''

Revision as of 08:39, 20 March 2008


PDB ID 1dir

Drag the structure with the mouse to rotate
, resolution 2.60Å
Ligands:
Activity: 6,7-dihydropteridine reductase, with EC number 1.5.1.34
Coordinates: save as pdb, mmCIF, xml



CRYSTAL STRUCTURE OF A MONOCLINIC FORM OF DIHYDROPTERIDINE REDUCTASE FROM RAT LIVER


Overview

A binary complex of dihydropteridine reductase and NADH crystallizes in the space group C2, with a = 222.2, b = 46.5, c = 95.3 A and beta = 101.1 degrees. There are two dimers in the asymmetric unit. The structure was solved by molecular-replacement techniques and refined with 2.6 A data to a crystallographic R factor of 16.8%. Each dimer has twofold non-crystallographic symmetry and the four individual monomers in the asymmetric unit have the same overall molecular conformation.

About this Structure

1DIR is a Single protein structure of sequence from Rattus norvegicus. Full crystallographic information is available from OCA.

Reference

Crystal structure of a monoclinic form of dihydropteridine reductase from rat liver., Su Y, Skinner MM, Xuong NH, Matthews DA, Whiteley JM, Varughese KI, Acta Crystallogr D Biol Crystallogr. 1994 Nov 1;50(Pt 6):884-8. PMID:15299357

Page seeded by OCA on Thu Mar 20 10:39:03 2008

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