1bn0

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[[Image:1bn0.png|left|200px]]
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==SL3 HAIRPIN FROM THE PACKAGING SIGNAL OF HIV-1, NMR, 11 STRUCTURES==
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<StructureSection load='1bn0' size='340' side='right' caption='[[1bn0]], [[NMR_Ensembles_of_Models | 11 NMR models]]' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1bn0]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BN0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1BN0 FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1bn0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1bn0 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1bn0 RCSB], [http://www.ebi.ac.uk/pdbsum/1bn0 PDBsum]</span></td></tr>
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<table>
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<div style="background-color:#fffaf0;">
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== Publication Abstract from PubMed ==
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An NMR-based structure is presented for a 20 mer hairpin model of the SL3 stem-loop from the HIV-1 packaging signal. The stem has an A-family structure. However, the GGAG tetraloop appears to be flexible with the second (G10) and fourth (G12) bases extruded from the normal stacking arrangement. The A-base (A11) occupies a cavity large enough for it to jump rapidly between stacking upon G9 (in the loop) and G13 (from the base-pair adjacent to the loop). The H-bonding loci of G10, A11, and G12 are unoccupied in the free RNA structure. The loop should be easily adaptable to binding by the HIV-1 nucleocapsid protein or loop receptors.
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{{STRUCTURE_1bn0| PDB=1bn0 | SCENE= }}
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Three-dimensional folding of an RNA hairpin required for packaging HIV-1.,Pappalardo L, Kerwood DJ, Pelczer I, Borer PN J Mol Biol. 1998 Oct 2;282(4):801-18. PMID:9743628<ref>PMID:9743628</ref>
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===SL3 HAIRPIN FROM THE PACKAGING SIGNAL OF HIV-1, NMR, 11 STRUCTURES===
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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</div>
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{{ABSTRACT_PUBMED_9743628}}
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== References ==
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<references/>
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==About this Structure==
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__TOC__
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[[1bn0]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BN0 OCA].
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</StructureSection>
[[Category: Borer, P N.]]
[[Category: Borer, P N.]]
[[Category: Kerwood, D J.]]
[[Category: Kerwood, D J.]]

Revision as of 09:34, 13 August 2014

SL3 HAIRPIN FROM THE PACKAGING SIGNAL OF HIV-1, NMR, 11 STRUCTURES

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