1bvj

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[[Image:1bvj.png|left|200px]]
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==HIV-1 RNA A-RICH HAIRPIN LOOP==
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<StructureSection load='1bvj' size='340' side='right' caption='[[1bvj]], [[NMR_Ensembles_of_Models | 21 NMR models]]' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1bvj]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Viruses Viruses]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BVJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1BVJ FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1bvj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1bvj OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1bvj RCSB], [http://www.ebi.ac.uk/pdbsum/1bvj PDBsum]</span></td></tr>
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<table>
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<div style="background-color:#fffaf0;">
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== Publication Abstract from PubMed ==
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Interaction of HIV-1 genomic RNA and human tRNA(Lys)3 initiates viral reverse transcription. An adenosine-rich (A-rich) loop in HIV RNA mediates complex formation between tRNA and viral RNA. We have determined the structure of an A-rich loop oligonucleotide using nuclear magnetic resonance spectroscopy. The loop structure is stabilized by a noncanonical G-A pair and a U-turn motif, which leads to stacking of the conserved adenosines. The structure has similarity to the tRNA anticodon structure, and suggests possible mechanisms for its role in initiation of reverse transcription.
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{{STRUCTURE_1bvj| PDB=1bvj | SCENE= }}
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HIV-1 A-rich RNA loop mimics the tRNA anticodon structure.,Puglisi EV, Puglisi JD Nat Struct Biol. 1998 Dec;5(12):1033-6. PMID:9846871<ref>PMID:9846871</ref>
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===HIV-1 RNA A-RICH HAIRPIN LOOP===
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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</div>
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{{ABSTRACT_PUBMED_9846871}}
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== References ==
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<references/>
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==About this Structure==
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__TOC__
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[[1bvj]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Viruses Viruses]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BVJ OCA].
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</StructureSection>
[[Category: Viruses]]
[[Category: Viruses]]
[[Category: Puglisi, E V.]]
[[Category: Puglisi, E V.]]

Revision as of 09:48, 13 August 2014

HIV-1 RNA A-RICH HAIRPIN LOOP

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