Epidermal growth factor
From Proteopedia
(Difference between revisions)
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'''Epidermal growth factor''' (EGF) plays a role in cell growth. It binds to its receptor ([[Epidermal Growth Factor Receptor|EGFR]]). EGF is regulated by iodine. EGF is part of a family of proteins with similar structure and activity. All EGF family proteins contain a conserved amino acid sequence which includes 3 disulfide bonds. Some details on EGF exon in [[EGF1]]. | '''Epidermal growth factor''' (EGF) plays a role in cell growth. It binds to its receptor ([[Epidermal Growth Factor Receptor|EGFR]]). EGF is regulated by iodine. EGF is part of a family of proteins with similar structure and activity. All EGF family proteins contain a conserved amino acid sequence which includes 3 disulfide bonds. Some details on EGF exon in [[EGF1]]. | ||
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==3D structures of epidermal growth factor== | ==3D structures of epidermal growth factor== | ||
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[[1jl9]] – hEGF<br/ > | [[1jl9]] – hEGF<br/ > | ||
[[2kv4]] – hEGF - NMR<br/ > | [[2kv4]] – hEGF - NMR<br/ > | ||
| - | [[1gk5]], [[1p9j]] – hEGF/transforming growth factor alpha - NMR | + | [[1gk5]], [[1p9j]] – hEGF/transforming growth factor alpha - NMR<br /> |
| + | [[1ivo]], [[1nql]] – hEGF + EGFR<br /> | ||
===Heparin-binding EGF-like growth factor=== | ===Heparin-binding EGF-like growth factor=== | ||
Revision as of 07:03, 14 August 2014
Epidermal growth factor (EGF) plays a role in cell growth. It binds to its receptor (EGFR). EGF is regulated by iodine. EGF is part of a family of proteins with similar structure and activity. All EGF family proteins contain a conserved amino acid sequence which includes 3 disulfide bonds. Some details on EGF exon in EGF1.
3D structures of epidermal growth factor
Updated on 14-August-2014
1egf, 1epg, 1eph, 1epi, 1epj, 3egf – mEGF – mouse – NMR
1a3p – mEGF (mutant) – NMR
1jl9 – hEGF
2kv4 – hEGF - NMR
1gk5, 1p9j – hEGF/transforming growth factor alpha - NMR
1ivo, 1nql – hEGF + EGFR
Heparin-binding EGF-like growth factor
1xdt – hHB-EGF extracellular domain + diphtheria toxin
EGF-like Cripto protein
2j5h – mCR-EGF residues 96-134 - NMR
