Annexin
From Proteopedia
| Line 1: | Line 1: | ||
[[Image:1ain.png|left|200px|thumb|Crystal Structure of Human Annexin I, [[1ain]]]] | [[Image:1ain.png|left|200px|thumb|Crystal Structure of Human Annexin I, [[1ain]]]] | ||
{{STRUCTURE_1ain| PDB=1ain | SIZE=400| SCENE=Annexin/Cv/2 |right|CAPTION=Human annexin I complex with Ca+2 ions, [[1ain]] }} | {{STRUCTURE_1ain| PDB=1ain | SIZE=400| SCENE=Annexin/Cv/2 |right|CAPTION=Human annexin I complex with Ca+2 ions, [[1ain]] }} | ||
| - | __NOTOC__ | ||
| Line 35: | Line 34: | ||
Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} | Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} | ||
| - | == Annexin I == | + | === Annexin I === |
[[2q4c]], [[1ycn]] - AnI - ''Arabidopsis thaliana''<br /> | [[2q4c]], [[1ycn]] - AnI - ''Arabidopsis thaliana''<br /> | ||
| Line 43: | Line 42: | ||
[[1ain]] - hAnI<br /> | [[1ain]] - hAnI<br /> | ||
| - | == Annexin II == | + | === Annexin II === |
[[2hyu]], [[2hyv]] - hAnII+heparin oligosaccharide<br /> | [[2hyu]], [[2hyv]] - hAnII+heparin oligosaccharide<br /> | ||
| Line 50: | Line 49: | ||
[[1bt6]] - hAnII head+calpactin light chain<br /> | [[1bt6]] - hAnII head+calpactin light chain<br /> | ||
| - | == Annexin III == | + | === Annexin III === |
[[1aii]], [[1axn]] - hAnIII<br /> | [[1aii]], [[1axn]] - hAnIII<br /> | ||
| - | == Annexin IV == | + | === Annexin IV === |
[[2zhi]], [[2zhj]], rAnIV+Na - rat<br /> | [[2zhi]], [[2zhj]], rAnIV+Na - rat<br /> | ||
| Line 61: | Line 60: | ||
[[1aow]], [[1ann]] - cAnIV<br /> | [[1aow]], [[1ann]] - cAnIV<br /> | ||
| - | == Annexin V == | + | === Annexin V === |
[[2ie6]], [[2ie7]], rAnV<br /> | [[2ie6]], [[2ie7]], rAnV<br /> | ||
| Line 79: | Line 78: | ||
[[2xo3]] - hAnV + Ca + homopropargylglycine | [[2xo3]] - hAnV + Ca + homopropargylglycine | ||
| - | == Annexin VI == | + | === Annexin VI === |
[[1m9i]] - hAnVI (mutant)<br /> | [[1m9i]] - hAnVI (mutant)<br /> | ||
[[1avc]] - cAnVI+Ca<br /> | [[1avc]] - cAnVI+Ca<br /> | ||
| - | == Annexin VIII == | + | === Annexin VIII === |
[[1w3w]] - hAnVIII<br /> | [[1w3w]] - hAnVIII<br /> | ||
[[1w45]] - hAnVIII (mutant)<br /> | [[1w45]] - hAnVIII (mutant)<br /> | ||
| - | == Annexin XII == | + | === Annexin XII === |
[[1dm5]] - HvAnXII (mutant) - ''Hydra vulgaris''<br /> | [[1dm5]] - HvAnXII (mutant) - ''Hydra vulgaris''<br /> | ||
[[1aei]] - HvAnXII<br /> | [[1aei]] - HvAnXII<br /> | ||
| - | == Annexin E1 == | + | === Annexin E1 === |
[[3chj]] – GlAnE1 – ''Giardia lamblia''<br /> | [[3chj]] – GlAnE1 – ''Giardia lamblia''<br /> | ||
[[3chk]], [[3chl]] – GlAnE1 + cation | [[3chk]], [[3chl]] – GlAnE1 + cation | ||
| - | == Other annexins == | + | === Other annexins === |
[[1dk5]] - An24 - ''Capsicom annuum''<br /> | [[1dk5]] - An24 - ''Capsicom annuum''<br /> | ||
Revision as of 09:21, 14 August 2014
Annexins are proteins which make a membrane scaffold. They bind negatively charged phospholipids and contain a 70 amino acid long annexin repeat. They consist of 2 domains - the C-terminal core and the N-terminal head. Annexins divide into species and are numbered from I to XII. Annexin V is the most abundant scaffolding protein. Annexin E1 (AnE1) is associated with tubulin in trophozoites of Giardia lamblia and forms local slubs in the flagella. In the annexin image calcium ions are shown as green balls.
Contents |
3D structures of annexin
Updated on 14-August-2014
Annexin I
2q4c, 1ycn - AnI - Arabidopsis thaliana
1mcx, 1hm6 - pAnI - pig
1qls - pAnI head+calgizzarrin
1bo9 - hAnI head - human NMR
1ain - hAnI
Annexin II
2hyu, 2hyv - hAnII+heparin oligosaccharide
2hyw, 1xjl - hAnII+Ca
1w7b - hAnII
1bt6 - hAnII head+calpactin light chain
Annexin III
Annexin IV
2zhi, 2zhj, rAnIV+Na - rat
2zoc - hAnIV
1i4a - cAnIV (mutant) - cow
1aow, 1ann - cAnIV
Annexin V
2ie6, 2ie7, rAnV
1n41, 1n42, 1n44, 2h0k, 2h0l, 2h0m, 1bc0, 1bc1, 1bc3, 1bcw, 1bcy, 1bcz - rAnV (mutant)
1g5n - rAnV+ heparin oligosaccharide
1a8a, 1a8b - rAnV+phospholipid analog
2ran - rAnV+Ca
1yii – chAnV+Ca – chicken
1yj0 - chAnV+Zn
1ala - ChAnV
1hak - hAnV+K-201
1sav - hAnV (thioproline)
1hvd, 1hve, 1hvf, 1hvg - hAnV (mutant)
1anw, 1avh, 1avr - hAnV
1anx - hAnV+Ca
2xo2 – hAnV + Ca + azidohomoalanine
2xo3 - hAnV + Ca + homopropargylglycine
Annexin VI
1m9i - hAnVI (mutant)
1avc - cAnVI+Ca
Annexin VIII
1w3w - hAnVIII
1w45 - hAnVIII (mutant)
Annexin XII
1dm5 - HvAnXII (mutant) - Hydra vulgaris
1aei - HvAnXII
Annexin E1
3chj – GlAnE1 – Giardia lamblia
3chk, 3chl – GlAnE1 + cation
Other annexins
1dk5 - An24 - Capsicom annuum
3brx - coAnGH1+Ca - cotton
1n00 - coAnGH1
