Factor VIII
From Proteopedia
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{{STRUCTURE_2r7e| PDB=2r7e | SIZE=400| SCENE=Factor_VIII/Cv/1 |right|CAPTION=Glycosylated human Factor VIII. Residues 19-760 (grey) 1582-2351 (green) complex with Ca+2 (green) and Cu+2 (orange) ions, [[2r7e]] }} | {{STRUCTURE_2r7e| PDB=2r7e | SIZE=400| SCENE=Factor_VIII/Cv/1 |right|CAPTION=Glycosylated human Factor VIII. Residues 19-760 (grey) 1582-2351 (green) complex with Ca+2 (green) and Cu+2 (orange) ions, [[2r7e]] }} | ||
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[[Factor VIII]] (FVIII) is a blood clotting factor. Defects in the protein result in hemophilia A. FVIII is a cofactor for [[Factor IX|factor IXa]]. The images at the left and at the right correspond to one representative FVIII, ''i.e.'' the crystal structure of human Factor VIII ([[2r7e]]). | [[Factor VIII]] (FVIII) is a blood clotting factor. Defects in the protein result in hemophilia A. FVIII is a cofactor for [[Factor IX|factor IXa]]. The images at the left and at the right correspond to one representative FVIII, ''i.e.'' the crystal structure of human Factor VIII ([[2r7e]]). | ||
Revision as of 06:52, 18 August 2014
Factor VIII (FVIII) is a blood clotting factor. Defects in the protein result in hemophilia A. FVIII is a cofactor for factor IXa. The images at the left and at the right correspond to one representative FVIII, i.e. the crystal structure of human Factor VIII (2r7e).
Contents |
3D Structures of Factor VIII
Updated on 18-August-2014
2r7e, 3cdz, 3j2q, 4bdv – hFVIII – human
3hnb, 3hny, 3hob – hFVIII light chain C2 domain
1d7p - hFVIII light chain C2 domain (mutant)
1cfg, 1fac - hFVIII light chain C2 domain membrane-binding peptide - NMR
1iqd - hFVIII light chain C2 domain (mutant) + monoclonal Fab
4ki5 - mFVIII light chain C2 domain + monoclonal Fab – mouse
3j2s - hFVIII light chain
4mo3 - FVIII light chain C2 domain – pig
