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Nitrate reductase
From Proteopedia
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Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} | Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} | ||
| - | + | ===Bacterial periplasmic dissimilatory NR=== | |
[[2nap]], [[2jim]], [[2jio]], [[2jip]], [[2v3v]], [[2v45]] – DdNAP + MGD + Mo - ''Desulfovibrio desulfuricans''<br /> | [[2nap]], [[2jim]], [[2jio]], [[2jip]], [[2v3v]], [[2v45]] – DdNAP + MGD + Mo - ''Desulfovibrio desulfuricans''<br /> | ||
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[[3ml1]], [[3o5a]] - NAP catalytic subunit + NAPB + heme + MGD + Mo – ''Ralstonia eutropha'' | [[3ml1]], [[3o5a]] - NAP catalytic subunit + NAPB + heme + MGD + Mo – ''Ralstonia eutropha'' | ||
| - | + | ===Bacterial respiratory NR=== | |
[[1q16]], [[1y5l]] – EcNAR α+β+γ chains + heme + MGD + Mo<br /> | [[1q16]], [[1y5l]] – EcNAR α+β+γ chains + heme + MGD + Mo<br /> | ||
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[[3ir6]] - EcNAR α (mutant) +β + γ chains + inhibitor + heme + GDP | [[3ir6]] - EcNAR α (mutant) +β + γ chains + inhibitor + heme + GDP | ||
| - | + | ===Eukaryotic assimilatory NR=== | |
[[2bih]], [[2bii]] – NR MoCo-binding domain + MPT – ''Pichia angusta'' | [[2bih]], [[2bii]] – NR MoCo-binding domain + MPT – ''Pichia angusta'' | ||
[[Category:Topic Page]] | [[Category:Topic Page]] | ||
Revision as of 09:01, 19 August 2014
Nitrate reductase (NR) catalyzes the reduction of NO3 to NO2 using NADPH . NR active site contains Mo atom. Four types of NR are known: one eukaryotic assimilatory NR and 3 bacterial NRs – cytoplasmic assimilatory (NAC), membrane-bound respiratory (NAR) and periplasmic dissimilatory (NAP). The cofactors of NR are Molybdopterin (MPT) in eukaryotic NR and bis-Molybdopterin guanine dinucleotide (MGD) in bacterial NR.
Contents |
3D structures of nitrate reductase
Updated on 19-August-2014
Bacterial periplasmic dissimilatory NR
2nap, 2jim, 2jio, 2jip, 2v3v, 2v45 – DdNAP + MGD + Mo - Desulfovibrio desulfuricans
2jiq - DdNAP + NO3 + MGD + Mo
2jir - DdNAP + CN + MGD + Mo
1jni – NAP small subunit + heme – Haemophilus influenzae
1ogy - NAP + heme + MGD + Mo– Rhodobacter sphaeroides
2nya - EcNAP + MGD + Mo – Escherichia coli
3ml1, 3o5a - NAP catalytic subunit + NAPB + heme + MGD + Mo – Ralstonia eutropha
Bacterial respiratory NR
1q16, 1y5l – EcNAR α+β+γ chains + heme + MGD + Mo
1r27 - EcNAR α+β chains + MGD + Mo
1siw – EcNAR α+β+γ chains + heme
1y4z, 3egw - EcNAR α+β (mutant) + γ chains + inhibitor + heme + MGD + Mo
1y5i, 1y5n - EcNAR α+β + γ (mutant) chains + inhibitor + heme + MGD + Mo
3ir5, 3ir7 - EcNAR α (mutant) +β + γ chains + inhibitor + heme + MGD + Mo
3ir6 - EcNAR α (mutant) +β + γ chains + inhibitor + heme + GDP
Eukaryotic assimilatory NR
2bih, 2bii – NR MoCo-binding domain + MPT – Pichia angusta
