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Opioid receptor
From Proteopedia
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<StructureSection load='4djh' size='350' side='right' caption='Structure of κ-opioid receptor complex with opioid antagonist, citric acid, PEG and octadec-enoate derivative (PDB entry [[4djh]])' scene=''> | <StructureSection load='4djh' size='350' side='right' caption='Structure of κ-opioid receptor complex with opioid antagonist, citric acid, PEG and octadec-enoate derivative (PDB entry [[4djh]])' scene=''> | ||
| - | '''Opioid receptor''' (OpR) is a G protein-coupled receptor with opioids as ligands. OpR types are classified according to the ligands which bind to them. The '''μ-opioid receptor''' binds morphine | + | '''Opioid receptor''' (OpR) is a G protein-coupled receptor with opioids as ligands. OpR types are classified according to the ligands which bind to them.<br /> |
| + | * The '''μ-opioid receptor''' binds morphine. For more details on μ-opioid receptor see [[Mu Opioid Receptor Bound to a Morphinan Antagonist]].<br /> | ||
| + | * The '''κ-opioid receptor''' binds opium-type ligands.<br /> | ||
| + | * The '''δ-opioid receptor''' binds enkephalins. | ||
==3D structures of opioid receptor== | ==3D structures of opioid receptor== | ||
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Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} | Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} | ||
| - | + | ===δ-opioid receptor=== | |
[[4ej4]] – mOpR + naltrindole - mouse <br /> | [[4ej4]] – mOpR + naltrindole - mouse <br /> | ||
| - | + | ===κ-opioid receptor=== | |
[[4djh]] – hOpR + opioid antagonist - human <br /> | [[4djh]] – hOpR + opioid antagonist - human <br /> | ||
| - | + | ===Nociceptin/orphanin FQ opioid receptor=== | |
[[4ea3]] – hOpR + peptide mimetic <br /> | [[4ea3]] – hOpR + peptide mimetic <br /> | ||
| - | + | ===μ-opioid receptor'=== | |
[[4dkl]] – mOpR + opioid antagonist <br /> | [[4dkl]] – mOpR + opioid antagonist <br /> | ||
[[Category:Topic Page]] | [[Category:Topic Page]] | ||
Revision as of 09:24, 19 August 2014
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