1dnm

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[[Image:1dnm.gif|left|200px]]<br /><applet load="1dnm" size="350" color="white" frame="true" align="right" spinBox="true"
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[[Image:1dnm.gif|left|200px]]
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caption="1dnm, resolution 2.500&Aring;" />
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'''CRYSTAL STRUCTURE AND SEQUENCE-DEPENDENT CONFORMATION OF THE A.G MIS-PAIRED OLIGONUCLEOTIDE D(CGCAAGCTGGCG)'''<br />
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{{Structure
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|PDB= 1dnm |SIZE=350|CAPTION= <scene name='initialview01'>1dnm</scene>, resolution 2.500&Aring;
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|SITE=
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|LIGAND=
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|ACTIVITY=
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|GENE=
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}}
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'''CRYSTAL STRUCTURE AND SEQUENCE-DEPENDENT CONFORMATION OF THE A.G MIS-PAIRED OLIGONUCLEOTIDE D(CGCAAGCTGGCG)'''
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==Overview==
==Overview==
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==About this Structure==
==About this Structure==
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1DNM is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/ ]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DNM OCA].
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1DNM is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/ ]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DNM OCA].
==Reference==
==Reference==
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Crystal structure and sequence-dependent conformation of the A.G mispaired oligonucleotide d(CGCAAGCTGGCG)., Webster GD, Sanderson MR, Skelly JV, Neidle S, Swann PF, Li BF, Tickle IJ, Proc Natl Acad Sci U S A. 1990 Sep;87(17):6693-7. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=2395870 2395870]
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Crystal structure and sequence-dependent conformation of the A.G mispaired oligonucleotide d(CGCAAGCTGGCG)., Webster GD, Sanderson MR, Skelly JV, Neidle S, Swann PF, Li BF, Tickle IJ, Proc Natl Acad Sci U S A. 1990 Sep;87(17):6693-7. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/2395870 2395870]
[[Category: Protein complex]]
[[Category: Protein complex]]
[[Category: Li, B F.]]
[[Category: Li, B F.]]
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[[Category: mismatched]]
[[Category: mismatched]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 12:18:28 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 10:41:23 2008''

Revision as of 08:41, 20 March 2008

Image:1dnm.gif


PDB ID 1dnm

Drag the structure with the mouse to rotate
, resolution 2.500Å
Coordinates: save as pdb, mmCIF, xml



CRYSTAL STRUCTURE AND SEQUENCE-DEPENDENT CONFORMATION OF THE A.G MIS-PAIRED OLIGONUCLEOTIDE D(CGCAAGCTGGCG)


Overview

The crystal structure of the dodecanucleotide d(CGCAAGCTGGCG) has been determined to a resolution of 2.5 A and refined to an R factor of 19.3% for 1710 reflections. The sequence crystallizes as a B-type double helix, with two G(anti).A(syn) base pairs. These are stabilized by three-center hydrogen bonds to pyrimidines that induce perturbations in base-pair geometry. The central AGCT region of the helix has a wide (greater than 6 A) minor groove.

About this Structure

1DNM is a Protein complex structure of sequences from [1]. Full crystallographic information is available from OCA.

Reference

Crystal structure and sequence-dependent conformation of the A.G mispaired oligonucleotide d(CGCAAGCTGGCG)., Webster GD, Sanderson MR, Skelly JV, Neidle S, Swann PF, Li BF, Tickle IJ, Proc Natl Acad Sci U S A. 1990 Sep;87(17):6693-7. PMID:2395870

Page seeded by OCA on Thu Mar 20 10:41:23 2008

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