Plasminogen
From Proteopedia
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'''Plasmin''' (PLN) is a serine protease which is involved in degradation of fibrin clots. PLN is released as the zymogen '''plasminogen''' (PLG) which is converted to the active PLN by a variety of enzymes. PLN cleavage produces angiostatin. PLN domains are: N-terminal, C-terminal serine protease catalytic domain and 5 kringle domains of ca. 80 residues. | '''Plasmin''' (PLN) is a serine protease which is involved in degradation of fibrin clots. PLN is released as the zymogen '''plasminogen''' (PLG) which is converted to the active PLN by a variety of enzymes. PLN cleavage produces angiostatin. PLN domains are: N-terminal, C-terminal serine protease catalytic domain and 5 kringle domains of ca. 80 residues. | ||
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== 3D Structures of plasminogen == | == 3D Structures of plasminogen == | ||
Revision as of 06:48, 20 August 2014
Plasmin (PLN) is a serine protease which is involved in degradation of fibrin clots. PLN is released as the zymogen plasminogen (PLG) which is converted to the active PLN by a variety of enzymes. PLN cleavage produces angiostatin. PLN domains are: N-terminal, C-terminal serine protease catalytic domain and 5 kringle domains of ca. 80 residues.
Contents |
3D Structures of plasminogen
Updated on 20-August-2014
Plasminogen kringle 1
1pkr - hPLG kringle 1 – human
1cea - hPLG kringle 1 + e-aminocaprioic acid
1hpj, 1hpk - hPLG kringle 1 + 6-aminohexanoic acid - NMR
1ceb - hPLG kringle 1 + AMCHA
Plasminogen kringle 2
1b2i - hPLG kringle 2 (mutant) – NMR
1i5k - hPLG kringle 2 (mutant) + M2 protein peptide
2kj4 – hPLG kringle 2 + M2 protein peptide – NMR
Plasminogen kringle 3
2l0s - hPLG kringle 3 – NMR
Plasminogen kringle 4
1pk4, 1pmk, 1pml, 1krn – hPLG kringle 4
2pk4 - hPLG kringle 4 + e-aminocaprioic acid
Plasminogen kringle 5
5hpg - hPLG kringle 5
2knf - hPLG kringle 5 – NMR
Plasminogen catalytic domain
1qrz, 1ddj, 1rjx – hPLG catalytic domain (mutant)
1l4d, 1l4z - hPLG catalytic domain (mutant) + streptokinase α domain
Plasmin
1bml – hPLN catalytic domain + streptokinase
1bui – hPLN light chain + staphylokinase
Microplasmin
3uir – hPLN + textilinin-1
