Plasminogen activator inhibitor
From Proteopedia
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{{STRUCTURE_1c5g| PDB=1c5g | SIZE=400| SCENE= |right|CAPTION=Human plasminogen activator inhibitor 1, [[1c5g]] }} | {{STRUCTURE_1c5g| PDB=1c5g | SIZE=400| SCENE= |right|CAPTION=Human plasminogen activator inhibitor 1, [[1c5g]] }} | ||
| - | '''Plasminogen activator inhibitor''' (PAI) is a serine protease inhibitor. PAI-1 inhibits tissue plasminogen activator and urokinase. PAI-2 is secreted by the placenta and is present during pregnancy. PAI-3 inhibits enzymes in blood coagulation. | + | '''Plasminogen activator inhibitor''' (PAI) is a serine protease inhibitor.<br /> |
| - | + | * '''PAI-1''' inhibits tissue plasminogen activator and urokinase.<br /> | |
| - | + | * '''PAI-2''' is secreted by the placenta and is present during pregnancy.<br /> | |
| + | * '''PAI-3''' inhibits enzymes in blood coagulation. | ||
== 3D Structures of plasminogen activator inhibitor == | == 3D Structures of plasminogen activator inhibitor == | ||
Revision as of 06:50, 20 August 2014
Plasminogen activator inhibitor (PAI) is a serine protease inhibitor.
- PAI-1 inhibits tissue plasminogen activator and urokinase.
- PAI-2 is secreted by the placenta and is present during pregnancy.
- PAI-3 inhibits enzymes in blood coagulation.
Contents |
3D Structures of plasminogen activator inhibitor
Updated on 20-August-2014
PAI-1
1c5g, 1lj5 - hPAI-1 – human
1b3k, 1db2, 1dvm, 1dvn, 3cvm, 3eox, 3q02, 3q03, 3r4l - hPAI-1 (mutant)
1a7c, 9pai – hPAI-1 (mutant) + polypeptide
4g8r, 4g8o – hPAI-1 + inactivator
4ic0 - hPAI-1 (mutant) + gallate
3ut3 - hPAI-1 (mutant) + inhibitor
3aqh - hPAI-1 + inhibitor
1oc0 - hPAI-1 (mutant) + vitronectin
3pb1 - hPAI-1 (mutant) + urokinase (mutant)
3lw2 – PAI-1 - mouse
4kds – PAI-1 – trout
4dte – PAI-1 – zebra fish
PAI-2
1by7 - hPAI-2 (mutant)
1jrr, 2arq, 2arr - hPAI-2 (mutant) + polypeptide
PAI-3
2ol2 – hPAI-3
2hi9 - hPAI-3 residues 25-387
1lq8, 3dy0 – hPAI-3 cleaved
