SAGA-associated factor
From Proteopedia
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<StructureSection load='3mhs' size='350' side='right' caption='Structure of SGF11 (pink) in the SAGA complex with Sus1 (green) , SGF73 (magenta), ubiquitin (yellow) and UB8P (grey) (PDB entry [[3mhs]])' scene=''> | <StructureSection load='3mhs' size='350' side='right' caption='Structure of SGF11 (pink) in the SAGA complex with Sus1 (green) , SGF73 (magenta), ubiquitin (yellow) and UB8P (grey) (PDB entry [[3mhs]])' scene=''> | ||
| - | '''SAGA-associated factor''' (SGF) is part of the coactivator complex SAGA (Spt-Ada-Gcn5-Acetyl transferase) which facilitates transcription of stress-activated genes. SGF29 binds methylated lysine of histone H3 and is involved in transcriptional regulation. SGF11 is required for the deubiuqitination of histone H2B and for the maintenance of steady-state H3 methylation level. | + | '''SAGA-associated factor''' (SGF) is part of the coactivator complex SAGA (Spt-Ada-Gcn5-Acetyl transferase) which facilitates transcription of stress-activated genes.<br /> |
| + | * '''SGF29''' binds methylated lysine of histone H3 and is involved in transcriptional regulation.<br /> | ||
| + | * '''SGF11''' is required for the deubiuqitination of histone H2B and for the maintenance of steady-state H3 methylation level. | ||
==3D structures of SAGA-associated factor== | ==3D structures of SAGA-associated factor== | ||
Revision as of 08:56, 20 August 2014
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