Trichodiene synthase
From Proteopedia
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{{STRUCTURE_2q9z| PDB=2q9z | SIZE=350| SCENE= |right|CAPTION=Trichodiene synthase complex with diphosphate and Mg+2 ion (green) [[2q9z]] }} | {{STRUCTURE_2q9z| PDB=2q9z | SIZE=350| SCENE= |right|CAPTION=Trichodiene synthase complex with diphosphate and Mg+2 ion (green) [[2q9z]] }} | ||
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'''Trichodiene synthase''' (TCS) catalyzes the conversion of trans,trans-farnesyl diphosphate to trichodiene and diphosphate (PP). TCS belongs to the family of sesquiterpene syntases which cyclize the acyclic farnesyl diphosphate to a Sesquiterpene. TCS contains metalion-binding motifs. | '''Trichodiene synthase''' (TCS) catalyzes the conversion of trans,trans-farnesyl diphosphate to trichodiene and diphosphate (PP). TCS belongs to the family of sesquiterpene syntases which cyclize the acyclic farnesyl diphosphate to a Sesquiterpene. TCS contains metalion-binding motifs. |
Revision as of 07:42, 21 August 2014
Trichodiene synthase (TCS) catalyzes the conversion of trans,trans-farnesyl diphosphate to trichodiene and diphosphate (PP). TCS belongs to the family of sesquiterpene syntases which cyclize the acyclic farnesyl diphosphate to a Sesquiterpene. TCS contains metalion-binding motifs.
3D Structures of trichodiene synthase
Updated on 21-August-2014
1jfa – FsTCS – Fusarium sporotrichioides
1kiy, 1yj4, 2ps6 – FsTCS (mutant)
2aek, 2ps4, 2ps7 – FsTCS (mutant) + Mg
1jfg, 2q9z – FsTCS + PP + Mg
1kiz, 1yyq, 2ps5, 2ps8 – FsTCS (mutant) + PP + Mg
1yyr, 1yys, 1yyt, 1yyu, 2ael, 2aet – FsTCS (mutant) + PP + Mg + azabisabolene
2q9y – FsTCS + PP + Mg + benzyl triethyl ammonium