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Agrin
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{{STRUCTURE_3i70| PDB=3i70 | SIZE=400| SCENE=Agrin/Cv/1 |right|CAPTION=Chicken agrin, [[3i70]] }} | {{STRUCTURE_3i70| PDB=3i70 | SIZE=400| SCENE=Agrin/Cv/1 |right|CAPTION=Chicken agrin, [[3i70]] }} | ||
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[[Agrin]] (Agr) is involved in the embryogenesis of the neuromuscular junction. It is involved in the aggregation of acetylcholine receptors. Its N-terminal domain NtA binds laminin. The C-terminal of Agr has 3 laminin binding domains (LMB): G1-G3. The images at the left and at the right correspond to one representative Agrin, ''i.e.'' the crystal structure of chicken Agrin ([[3i70]]). | [[Agrin]] (Agr) is involved in the embryogenesis of the neuromuscular junction. It is involved in the aggregation of acetylcholine receptors. Its N-terminal domain NtA binds laminin. The C-terminal of Agr has 3 laminin binding domains (LMB): G1-G3. The images at the left and at the right correspond to one representative Agrin, ''i.e.'' the crystal structure of chicken Agrin ([[3i70]]). | ||
Revision as of 07:03, 24 August 2014
Agrin (Agr) is involved in the embryogenesis of the neuromuscular junction. It is involved in the aggregation of acetylcholine receptors. Its N-terminal domain NtA binds laminin. The C-terminal of Agr has 3 laminin binding domains (LMB): G1-G3. The images at the left and at the right correspond to one representative Agrin, i.e. the crystal structure of chicken Agrin (3i70).
3D Structures of Agrin
Updated on 24-August-2014
3i70, 1pxu – cNtA – chicken
1pz7, 1pz8, 1pz9 – cAgr
1q56 – cAgr LMB G3+Ca – NMR
1jb3, 1jc7 – cAgr LMB
3pve – Agr LMB G2 - mouse
3v65, 3v64 – Agr LMB G3 + Low-density lipoprotein receptor-related protein 4 - rat
