1dus

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[[Image:1dus.gif|left|200px]]<br /><applet load="1dus" size="350" color="white" frame="true" align="right" spinBox="true"
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[[Image:1dus.gif|left|200px]]
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caption="1dus, resolution 1.80&Aring;" />
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'''MJ0882-A hypothetical protein from M. jannaschii'''<br />
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{{Structure
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|PDB= 1dus |SIZE=350|CAPTION= <scene name='initialview01'>1dus</scene>, resolution 1.80&Aring;
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|SITE=
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|LIGAND=
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|ACTIVITY=
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|GENE=
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}}
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'''MJ0882-A hypothetical protein from M. jannaschii'''
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==Overview==
==Overview==
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==About this Structure==
==About this Structure==
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1DUS is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Methanocaldococcus_jannaschii Methanocaldococcus jannaschii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DUS OCA].
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1DUS is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Methanocaldococcus_jannaschii Methanocaldococcus jannaschii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DUS OCA].
==Reference==
==Reference==
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Structure-based experimental confirmation of biochemical function to a methyltransferase, MJ0882, from hyperthermophile Methanococcus jannaschii., Huang L, Hung L, Odell M, Yokota H, Kim R, Kim SH, J Struct Funct Genomics. 2002;2(3):121-7. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=12836702 12836702]
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Structure-based experimental confirmation of biochemical function to a methyltransferase, MJ0882, from hyperthermophile Methanococcus jannaschii., Huang L, Hung L, Odell M, Yokota H, Kim R, Kim SH, J Struct Funct Genomics. 2002;2(3):121-7. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12836702 12836702]
[[Category: Methanocaldococcus jannaschii]]
[[Category: Methanocaldococcus jannaschii]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: protein structure initiative]]
[[Category: protein structure initiative]]
[[Category: psi]]
[[Category: psi]]
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[[Category: structural genomics]]
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[[Category: structural genomic]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 12:20:40 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 10:44:42 2008''

Revision as of 08:44, 20 March 2008


PDB ID 1dus

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, resolution 1.80Å
Coordinates: save as pdb, mmCIF, xml



MJ0882-A hypothetical protein from M. jannaschii


Overview

We have determined the three-dimensional (3-D) structure of protein MJ0882, which derives from a hypothetical open reading frame in the genome of the hyperthermophile Methanococcus jannaschii. The 3-D fold of MJ0882 at 1.8 A highly resembles that of a methyltransferase, despite limited sequence similarity to any confirmed methyltransferase. The structure has an S-adenosylmethionine (AdoMet) binding pocket surrounded by motifs with similarities to those commonly found among AdoMet binding proteins. Preliminary biochemical experiments show that MJ0882 specifically binds to AdoMet, which is the essential co-factor for methyltransferases.

About this Structure

1DUS is a Single protein structure of sequence from Methanocaldococcus jannaschii. Full crystallographic information is available from OCA.

Reference

Structure-based experimental confirmation of biochemical function to a methyltransferase, MJ0882, from hyperthermophile Methanococcus jannaschii., Huang L, Hung L, Odell M, Yokota H, Kim R, Kim SH, J Struct Funct Genomics. 2002;2(3):121-7. PMID:12836702

Page seeded by OCA on Thu Mar 20 10:44:42 2008

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