1dxz
From Proteopedia
Line 1: | Line 1: | ||
- | [[Image:1dxz.gif|left|200px]] | + | [[Image:1dxz.gif|left|200px]] |
- | + | ||
- | '''M2 TRANSMEMBRANE SEGMENT OF ALPHA-SUBUNIT OF NICOTINIC ACETYLCHOLINE RECEPTOR FROM TORPEDO CALIFORNICA, NMR, 20 STRUCTURES''' | + | {{Structure |
+ | |PDB= 1dxz |SIZE=350|CAPTION= <scene name='initialview01'>1dxz</scene> | ||
+ | |SITE= | ||
+ | |LIGAND= <scene name='pdbligand=NH2:AMINO GROUP'>NH2</scene> | ||
+ | |ACTIVITY= | ||
+ | |GENE= | ||
+ | }} | ||
+ | |||
+ | '''M2 TRANSMEMBRANE SEGMENT OF ALPHA-SUBUNIT OF NICOTINIC ACETYLCHOLINE RECEPTOR FROM TORPEDO CALIFORNICA, NMR, 20 STRUCTURES''' | ||
+ | |||
==Overview== | ==Overview== | ||
Line 7: | Line 16: | ||
==About this Structure== | ==About this Structure== | ||
- | 1DXZ is a [ | + | 1DXZ is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Torpedo_californica Torpedo californica]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DXZ OCA]. |
==Reference== | ==Reference== | ||
- | Spatial structure of the M2 transmembrane segment of the nicotinic acetylcholine receptor alpha-subunit., Pashkov VS, Maslennikov IV, Tchikin LD, Efremov RG, Ivanov VT, Arseniev AS, FEBS Lett. 1999 Aug 20;457(1):117-21. PMID:[http:// | + | Spatial structure of the M2 transmembrane segment of the nicotinic acetylcholine receptor alpha-subunit., Pashkov VS, Maslennikov IV, Tchikin LD, Efremov RG, Ivanov VT, Arseniev AS, FEBS Lett. 1999 Aug 20;457(1):117-21. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/10486576 10486576] |
[[Category: Single protein]] | [[Category: Single protein]] | ||
[[Category: Torpedo californica]] | [[Category: Torpedo californica]] | ||
Line 25: | Line 34: | ||
[[Category: transmembrane segment]] | [[Category: transmembrane segment]] | ||
- | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 10:46:15 2008'' |
Revision as of 08:46, 20 March 2008
| |||||||
Ligands: | |||||||
Coordinates: | save as pdb, mmCIF, xml |
M2 TRANSMEMBRANE SEGMENT OF ALPHA-SUBUNIT OF NICOTINIC ACETYLCHOLINE RECEPTOR FROM TORPEDO CALIFORNICA, NMR, 20 STRUCTURES
Overview
A synthetic peptide corresponding to the transmembrane segment M2 (residues 236-267) of the alpha-subunit of the nicotinic acetylcholine receptor from Torpedo californica has been studied by two dimensional 1H-NMR spectroscopy in a chloroform-methanol (1:1) mixture containing 0.1 M LiClO4. Reconstruction of the spatial structure of M2 from the NMR data resulted in an alpha-helix formed by residues 241-263. Distribution of the molecular hydrophobicity potential on the helix surface is very similar to that in five-helix bundles of proteins with a known three dimensional structure: two hydrophilic bands located on the opposite helix sides separated by strong hydrophobic zones.
About this Structure
1DXZ is a Single protein structure of sequence from Torpedo californica. Full crystallographic information is available from OCA.
Reference
Spatial structure of the M2 transmembrane segment of the nicotinic acetylcholine receptor alpha-subunit., Pashkov VS, Maslennikov IV, Tchikin LD, Efremov RG, Ivanov VT, Arseniev AS, FEBS Lett. 1999 Aug 20;457(1):117-21. PMID:10486576
Page seeded by OCA on Thu Mar 20 10:46:15 2008