1dxz

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
-
[[Image:1dxz.gif|left|200px]]<br /><applet load="1dxz" size="350" color="white" frame="true" align="right" spinBox="true"
+
[[Image:1dxz.gif|left|200px]]
-
caption="1dxz" />
+
 
-
'''M2 TRANSMEMBRANE SEGMENT OF ALPHA-SUBUNIT OF NICOTINIC ACETYLCHOLINE RECEPTOR FROM TORPEDO CALIFORNICA, NMR, 20 STRUCTURES'''<br />
+
{{Structure
 +
|PDB= 1dxz |SIZE=350|CAPTION= <scene name='initialview01'>1dxz</scene>
 +
|SITE=
 +
|LIGAND= <scene name='pdbligand=NH2:AMINO GROUP'>NH2</scene>
 +
|ACTIVITY=
 +
|GENE=
 +
}}
 +
 
 +
'''M2 TRANSMEMBRANE SEGMENT OF ALPHA-SUBUNIT OF NICOTINIC ACETYLCHOLINE RECEPTOR FROM TORPEDO CALIFORNICA, NMR, 20 STRUCTURES'''
 +
 
==Overview==
==Overview==
Line 7: Line 16:
==About this Structure==
==About this Structure==
-
1DXZ is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Torpedo_californica Torpedo californica] with <scene name='pdbligand=NH2:'>NH2</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DXZ OCA].
+
1DXZ is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Torpedo_californica Torpedo californica]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DXZ OCA].
==Reference==
==Reference==
-
Spatial structure of the M2 transmembrane segment of the nicotinic acetylcholine receptor alpha-subunit., Pashkov VS, Maslennikov IV, Tchikin LD, Efremov RG, Ivanov VT, Arseniev AS, FEBS Lett. 1999 Aug 20;457(1):117-21. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=10486576 10486576]
+
Spatial structure of the M2 transmembrane segment of the nicotinic acetylcholine receptor alpha-subunit., Pashkov VS, Maslennikov IV, Tchikin LD, Efremov RG, Ivanov VT, Arseniev AS, FEBS Lett. 1999 Aug 20;457(1):117-21. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/10486576 10486576]
[[Category: Single protein]]
[[Category: Single protein]]
[[Category: Torpedo californica]]
[[Category: Torpedo californica]]
Line 25: Line 34:
[[Category: transmembrane segment]]
[[Category: transmembrane segment]]
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 12:21:44 2008''
+
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 10:46:15 2008''

Revision as of 08:46, 20 March 2008


PDB ID 1dxz

Drag the structure with the mouse to rotate
Ligands:
Coordinates: save as pdb, mmCIF, xml



M2 TRANSMEMBRANE SEGMENT OF ALPHA-SUBUNIT OF NICOTINIC ACETYLCHOLINE RECEPTOR FROM TORPEDO CALIFORNICA, NMR, 20 STRUCTURES


Overview

A synthetic peptide corresponding to the transmembrane segment M2 (residues 236-267) of the alpha-subunit of the nicotinic acetylcholine receptor from Torpedo californica has been studied by two dimensional 1H-NMR spectroscopy in a chloroform-methanol (1:1) mixture containing 0.1 M LiClO4. Reconstruction of the spatial structure of M2 from the NMR data resulted in an alpha-helix formed by residues 241-263. Distribution of the molecular hydrophobicity potential on the helix surface is very similar to that in five-helix bundles of proteins with a known three dimensional structure: two hydrophilic bands located on the opposite helix sides separated by strong hydrophobic zones.

About this Structure

1DXZ is a Single protein structure of sequence from Torpedo californica. Full crystallographic information is available from OCA.

Reference

Spatial structure of the M2 transmembrane segment of the nicotinic acetylcholine receptor alpha-subunit., Pashkov VS, Maslennikov IV, Tchikin LD, Efremov RG, Ivanov VT, Arseniev AS, FEBS Lett. 1999 Aug 20;457(1):117-21. PMID:10486576

Page seeded by OCA on Thu Mar 20 10:46:15 2008

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools