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Gramicidin

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<Structure load='2xds' size='400' scene= caption='Gramicidin D dimer with formyl-valine, formyl-isoleucine complex with PEG 1500 and ethanolamine , [[2xdc]]'/>
<Structure load='2xds' size='400' scene= caption='Gramicidin D dimer with formyl-valine, formyl-isoleucine complex with PEG 1500 and ethanolamine , [[2xdc]]'/>
[[Gramicidin]] (GCDN) is a polypeptide composed of alternating L- and D-amino acids. It has bactericidal activity and is used as antibiotic. It is produced by the bacteria ''Bacillus brevis''.<br />
[[Gramicidin]] (GCDN) is a polypeptide composed of alternating L- and D-amino acids. It has bactericidal activity and is used as antibiotic. It is produced by the bacteria ''Bacillus brevis''.<br />
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* '''GCDN S''' is a cyclic polypeptide.<br />
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* '''GCDN S''' is an antibiotic cyclic polypeptide.<br />
* '''GCDN D''' is a mixture of GCDN A, B, C. <br />
* '''GCDN D''' is a mixture of GCDN A, B, C. <br />
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* '''GCDN S''' is an antibiotic. <br />
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See theoretical model of [[Gramicidin Channel in Lipid Bilayer]].
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See theoretical model of [[Gramicidin Channel in Lipid Bilayer]].
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== 3D Structures of Gramicidin ==
== 3D Structures of Gramicidin ==

Revision as of 09:40, 27 August 2014

Gramicidin D dimer with formyl-valine, formyl-isoleucine complex with PEG 1500 and ethanolamine , 2xdc

Drag the structure with the mouse to rotate

Gramicidin (GCDN) is a polypeptide composed of alternating L- and D-amino acids. It has bactericidal activity and is used as antibiotic. It is produced by the bacteria Bacillus brevis.

  • GCDN S is an antibiotic cyclic polypeptide.
  • GCDN D is a mixture of GCDN A, B, C.

See theoretical model of Gramicidin Channel in Lipid Bilayer.

Contents

3D Structures of Gramicidin

Updated on 27-August-2014

Gramicidin A

1nt5, 1nt6, 1nrm, 1nru, 1ng8, 1kqe, 1jno, 1jo3, 1jo4, 1mic, 1mag, 1grm - GCDN A – NMR
1tkq - GCDN A + mini-GCDN A – NMR
1av2 - GCDN A + CsCl
1gmk - GCDN A + KCNS

Gramicidin D

2xdc, 1w5u, 1bdw, 1al4, 1alx, 1alz, 2y5m, 2y6n – GCDN D
3lml, 2izq, 3i8i, 3l8l - GCDN D + iodide
1c4d - GCDN D + CsCl
3zq8 – GCDN D + monovaccenin

Gramicidin S

1tk2 – GCDN S + subtilisin savinase – Bacillus lentus

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