Methane monooxygenase

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 3: Line 3:
== Function ==
== Function ==
-
'''Methane monooxygenase''' (MMO) catalyzes the oxidation of the C-H bond of methane and other alkanes. MMO catalyzes the conversion of CH4 and O2 to CH3OH and H2O using NADPH as reducing agent. The soluble MMO (sMMO) has Fe-O-Fe in its active site while the particulate MMO (pMMO) has Cu in it. MMO is composed of 3 subunits. Subunit α is the hydroxylase and contains the di-iron active site. Subunit β is a reductase which contains the co-factors FAD and 2Fe-2S complex. Subunit γ which is involved in coupling. MMO is found in methanotropic bacteria.
+
'''Methane monooxygenase''' (MMO) catalyzes the oxidation of the C-H bond of methane and other alkanes. MMO catalyzes the conversion of CH4 and O2 to CH3OH and H2O using NADPH as reducing agent. The '''soluble MMO (sMMO)''' has Fe-O-Fe in its active site while the '''particulate MMO (pMMO)''' has Cu in it. MMO is composed of 3 subunits.<br />
 +
* Subunit α is the hydroxylase and contains the di-iron active site.<br />
 +
* Subunit β is a reductase which contains the co-factors FAD and 2Fe-2S complex.<br />
 +
* Subunit γ which is involved in coupling.<br />
 +
MMO is found in methanotropic bacteria.
== Disease ==
== Disease ==

Revision as of 06:38, 2 September 2014

Structure of methane monooxygenase α (grey and green) +β (pink and yellow) +γ (magenta and cyan) subunits complex with Fe+3 (red), Ca+2 (green) and dibromomethane (PDB code 1fz8).

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel

Retrieved from "http://52.214.119.220/wiki/index.php/Methane_monooxygenase"
Personal tools