Nucleoporin
From Proteopedia
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[[Nucleoporin|Nucleoporins]] (NUP) are constituents of the nuclear pore complex which regulates the flow of macromolecules across the nuclear envelope. They are named according to their molecular weights. They contain a domain which binds the protein RAN (RANBD), N-terminal domain (NTD) and C-terminal domain (CTD). | [[Nucleoporin|Nucleoporins]] (NUP) are constituents of the nuclear pore complex which regulates the flow of macromolecules across the nuclear envelope. They are named according to their molecular weights. They contain a domain which binds the protein RAN (RANBD), N-terminal domain (NTD) and C-terminal domain (CTD). | ||
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== 3D Structures of Nucleoporin == | == 3D Structures of Nucleoporin == | ||
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===NUP2=== | ===NUP2=== | ||
[[3n7c]] – NUP2 RANBD – ''Ashbya gossypii''<br /> | [[3n7c]] – NUP2 RANBD – ''Ashbya gossypii''<br /> | ||
Revision as of 08:08, 2 September 2014
Template:STRUCTURE 1xip Nucleoporins (NUP) are constituents of the nuclear pore complex which regulates the flow of macromolecules across the nuclear envelope. They are named according to their molecular weights. They contain a domain which binds the protein RAN (RANBD), N-terminal domain (NTD) and C-terminal domain (CTD).
3D Structures of Nucleoporin
Updated on 02-September-2014
NUP2
3n7c – NUP2 RANBD – Ashbya gossypii
2c1t – yNUP2 NTD +importrin alpha subunit - yeast
NUP35
1wwh – mNUP35 MPPN domain - mouse
NUP37
4fhl – fyNUP37 – fission yeast
4fhm, 4fhn, 4gq2 - fyNUP37 + NUP120
NUP43
4i79 – hNUP43 + polypeptide
NUP50
2ec1 – hNUP50 RANBD - human
2c1m – mNUP50 NTD +importin
3tj3 - hNUP50 NTD+importin
NUP53
3p3d - NUP53 RRM domain - Pischia guillermondii
4lir – hNUP53 residues 151-266
NUP54
3t97 – rNUP54 + NUP62 - rat
4j3h – rNUP54 (mutant)
3t98 – rNUP54 + rNUP58/45
NUP58
2osz – rNUP58/45
NUP82
3pbp – yNUP82 NTD + NUP116 CTD + NUP159 tail
3tkn - yNUP82 NTD + NUP98 + NUP159 tail
NUP84
3jro, 3iko – yNUP84+NUP145+protein Sec13
NUP85
3f3f, 3f3g, 3f3p, 3ewe – yNUP85+Seh1
NUP98
3mmy – hNUP98 fragment+mRNA export factor
2q5x, 2q5y – hNUP98 CTD
1ko6 – hNUP98 CTD
NUP100
3nf5 – NUP100 CTD – Candida glabrata
NUP107
3i4r, 3cqc, 3cqg – hNUP107+NUP133
NUP116
2aiv – yNUP116 CTD - NMR
NUP120
NUP133
1xks – hNUP133 NTD
3kfo – yNUP133 CTD
NUP145
3bg0, 3bg1 – hNUP145+Sec13-related protein
3kep, 3kes – yNUP145 autoproteolytic domain
3jrp - yNUP145+protein Sec13
NUP153
3gj3, 3gj4, 3gj5, 3gj6, 3gj7, 3gj8, 3ch5 – hNUP153+RAN
2ebq, 2ebr, 2ebv, 2gqe - hNUP153 RANBD – NMR
2k0c – rNUP153 RANBD – NMR
NUP157
4mhc – hNUP157 NTD
NUP159
1xip – yNUP159 NTD
3rrm – yNUP159 residues 2-387 + NUP Gle1 + IP6 + ADP
NUP170
NUP192
4ifq – yNUP192
NUP214
3fmo, 3fmp, 3fhc – hNUP214+dead-box helicase
2oit – hNUP214 NTD
NUP358
1z5s – hNUP358 IR1 domain+ubiquitin-conjugating enzyme+SMT3C+RAN CTD
1xke - hNUP358 RANBD - NMR
NUP1P
2bpt – yNUP1P+importin β subunit
NUP2P
1un0 – yNUP2P NTD+importrin α subunit
NUP-NSP1
1o6o – yNUP-NSP1 residues 497-608+importrin β subunit
NUP-CDC31
2doq, 2gv5 – yNUP-CDC31+SFI1P
3fwb, 3fwc - yNUP-CDC31+SAC3
NUP Gle1
3peu, 3pev, 3rrn– yNUP-Gle1 + ATP-dependent RNA helicase Dbp5 (mutant) +IP6
2rfo, 2qx5 – yNic96
1gyb – NUP+yNTF2
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Michal Harel, Joel L. Sussman, Alexander Berchansky, Jaime Prilusky
