4pk6

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'''Unreleased structure'''
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==Crystal structure of the indoleamine 2,3-dioxygenagse 1 (IDO1) complexed with imidazothiazole derivative==
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<StructureSection load='4pk6' size='340' side='right' caption='[[4pk6]], [[Resolution|resolution]] 3.45&Aring;' scene=''>
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The entry 4pk6 is ON HOLD until Paper Publication
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4pk6]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4PK6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4PK6 FirstGlance]. <br>
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Authors: Kohno, T., Tojo, S., Ishii, T., Kamioka, S.
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=PKL:N-[2-(3-CHLOROPHENYL)ETHYL]-3-(4-METHYLPHENYL)IMIDAZO[2,1-B][1,3]THIAZOLE-5-CARBOXAMIDE'>PKL</scene><br>
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<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4pk5|4pk5]]</td></tr>
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Description: Crystal structure of the indoleamine 2,3-dioxygenagse 1 (IDO1) complexed with imidazothiazole derivative
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<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Indoleamine_2,3-dioxygenase Indoleamine 2,3-dioxygenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.13.11.52 1.13.11.52] </span></td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4pk6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4pk6 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4pk6 RCSB], [http://www.ebi.ac.uk/pdbsum/4pk6 PDBsum]</span></td></tr>
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<table>
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__TOC__
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</StructureSection>
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[[Category: Indoleamine 2,3-dioxygenase]]
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[[Category: Ishii, T.]]
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[[Category: Kamioka, S.]]
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[[Category: Kohno, T.]]
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[[Category: Tojo, S.]]
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[[Category: 3-dioxygenagse 1]]
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[[Category: Imidazothiazole]]
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[[Category: Indoleamine 2]]
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[[Category: Induced fit]]
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[[Category: Oxidoreductase-oxidoreductase inhibitor complex]]
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[[Category: Structure based drug discovery]]

Revision as of 06:10, 4 September 2014

Crystal structure of the indoleamine 2,3-dioxygenagse 1 (IDO1) complexed with imidazothiazole derivative

4pk6, resolution 3.45Å

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